FACULTY HIGHLIGHTED PUBLICATIONS

(Listed in chronological order)

McFadden K, Hafez AY, Kishton R, Messinger JE, Nikitin PA, Rathmell JC, Luftig MA (2016) Metabolic stress is a barrier to Epstein-Barr virus mediated B-cell immortalization. Proc Natl Acad Sci U S A 113:E782-90. [Article]

Meng L, Mulcahy B, Cook SJ, Neubauer M, Wan A, Jin Y, Yan D. The cell death pathway regulates synapse elimination through cleavage of celsolin in Caenorhabditis elegans neurons. Cell Rep, 11:1737-48.  2015. PMCID: PMC4481169. [EPub]

Kang D, Skalsky RL, Cullen BR. EBV BART microRNAs target multiple pro-apoptotic cellular genes to promote epithelial cell survival. PLoS Pathogens, 11, e1004979, 2015. [Epub]

Kokes M. Dunn JD, Granek JA, Nguyen BD, Barker JR, Valdivia RH, Bastidas RJ. Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia. Cell Host Microbe. 2015. [Epub]

Oehlers SH, Cronan MR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS,     Tobin DM. Interception of host angiogenic signalling limits mycobacterial growth. Nature 517: 612-15, 2015. [Epub]

Minchin_Rawls_PNAS_April 7 2015Minchin JN, Dahlman I, Harvey CJ, Mejhert N, Singh MK, Epstein JA, Arner P, Torres-Vázquez J and Rawls JF. Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in viseceral adipose tissue. Proc Natl Acad Sci USA 112(14): 4363-8. 22015, 2015. [Epub] Featured on  cover.

 

 

Silver J of Neuro Cover_May 6 2015Mao H, Pilaz LJ, McMahon J, Golzio C, Wu D, Shi L, Katsanis N and Silver DL Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly. Journal of Neuroscience. May 6; 35(18): 7003-7018, 2015. [Epub] Featured on cover.

 

 

Strope PK, Skelly DA, Kozmin SG, Mahadevan G, Stone EA, Magwene PM, Dietrich FS, McCusker JH. The 100-genomes strains, an S. cerevisiae resource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen. Genome Res. 2015 May;25(5):762-74. Doi: 10.1101/gr.185538.114. [Epub]

Jiang Y, Li YR, Tian H, Ma M, Matsunami H. Muscarinic acetylcholine receptor M3   modulates odorant receptor activity via inhibition of β-arrestin-2 recruitment. Nat Commun. 2015 Mar 24;6:6448. doi: 10.1038/ncomms7448. PubMed PMID: 25800153; PubMed Central PMCID: PMC4372811. [Epub]

Boyd JL, Skove SL, Rouanet JP, Pilaz L-J, Bepler T, Gordân R, Wray GA, and Silver DL. Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex. Current Biology. Mar 16; 25 (6) 772-9, 2015. [Epub]

Bogerd, H.P., Skalsky, R.L., Kennedy, E.M., Furuse, Y., Whisnant, A.W., Flores, O., Schultz, K.L., Putnam, N., Barrows, N.J., Sherry, B., Scholle, F., Garcia-Blanco, M.A., Griffin, D.E., and Cullen, B.R. (2014) Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs. J Virol, 88:8065-8076. [Abstract]

Chen YS, Bastidas RJ, Saka HA, Carpenter VK, Richards KL, Plano GV, Valdivia RH. The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling. PLoS Pathog. 2014 Feb 20;10(2):e1003954. doi: 10.1371/journal.ppat.1003954. PMID:  24586162 [Epub]

Engström P, Krishnan KS, Ngyuen BD, Chorell E, Normark J, Silver J, Bastidas RJ, Welch MD, Hultgren SJ, Wolf-Watz H, Valdivia RH, Almqvist F, Bergström S. A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis. MBio. 2014 PMID: 25550323 [Epub]

Snavely EA, Kokes M, Dunn JD, Saka HA, Nguyen BD, Bastidas RJ, McCafferty DG, Valdivia RH. Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches. Pathog Dis. 2014 PMID: 24838663 [Epub]

Cai Y, Cao X, and Aballay A. Whole-animal chemical screen identifies colistin as a new immunomodulator that targets conserved pathways. mBio, Aug 12;5(4). pii: e01235-14. doi: 10.1128/mBio.01235-14, 2014. [Epub]

Head B. and Aballay, A. Recovery from an acute infection in C. elegans requires the GATA transcription factor ELT-2. PLOS Genetics, Oct 23. doi: 10.1371/journal.pgen.1004609, 2014. [Epub]  [News Release]

Billmyre RB, Croll D, Li W, Mieczkowski P, Carter DA, Cuomo CA, Kronstad JW, Heitman J. Highly recombinant VGII Cryptococcus gatti population develops clonal outbreak clusters through both sexual macroevolution and asecual mecroevolution. mBio. 2014 Jul 29;5(4):e01494-14. doi: 10.1128/mBio.01494-14. [Epub]

Springer DJ, Billmyre RB, Filler EE, Voelz K, Pursall R, Mieczkowski PA, Larsen RA, Dietrich FS, May RC, Filler SG, Heitman J. Cryptococcus gattii VGII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environment source as arboreal. PLoS Pathog. 2014 Aug 21;10(8):e1004285. doi: 10.1371/journal.ppat.1004285. eCollection 2014 Aug. [Epub]

Calo S, Shertz-Wall C, Lee SC, Bastidas RJ, Nicolás FE, Granek JA, Mieczkowski P, Torres-Martínez S, Ruiz-Vázquez RM, Cardenas ME, Heitman J. Antifungl drug resistance evoked via RNAi-dependent epimutations. Nature. 2014 Sep 25;513(7519):555-8. doi: 10.1038/nature13575. [Epub]

Stimpson KM, Sullivan LL, Kuo ME, Sullivan BA. Nucleolar Organization, Ribosomal DNA Array Stability, and Acrocentric Chromosome Integrity Are Linked to Telomere Function. PLoS ONE 9(3): e92432. doi: 10.1371/journal.pone.0092432. 2014. [Epub]

Bogerd HP, Whisnant AW, Kennedy EM, Flores O and Cullen BR. Derivation and characterization of Dicer- and microRNA-deficient human cells. RNA, 20, 923-937. 2014. [Epub]

Friedersdorf M. and Keene JD. Advancing Functional Utility of PAR-CLIP by Quantifying Background Binding to mRNAs and lncRNAs. Genome Biology 15:R2. 2014. [Epub]

Cullen, B.R. (2014) Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs. J Virol, 88:8065-8076. [Abstract]

Song, W., Dominska, M., Greenwell, P. W., and Petes, T. (2014) Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae. Proc Nat Acad Sci, U S A, 111:E2210-8. [Abstract]

Pilla, D., Hagar, J.A., Haldar, A.K., Mason, A.K., Ernst, R.K., Yamamoto M., Miao, E.A., and Coers, J. (2014) Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. Proc Natl Acad Sci U S A, 111:6046-51. [Abstract]

Janbon, G. et al., and Dietrich, F.S. (2014) Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLOS Genetics, 10:e1004261. [Abstract]

Rawls_Camp_Frank_2014_GenResCamp, J.G., Frank, C.L., Lickwar, C.R., Guturu, H., Rube, T., Wenger, A.M., Chen, J. Bejerano, G., Crawford, G.E., and Rawls, J.F. (2014) Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape. Genome Res, Sep;24(9):1504-16 [Epub 2014 Jun 24]. [Abstract] Featured on the cover.

 

 

Mainland, J.D., Keller, A., Li, Y.R, Zhou, T., Snyder, L.L., Moberly, A.H., Adipietro, K.A., Liu, W.L.L., Zhuang, H., Zhan, S., Lee, S.S., Lin, A., and Matsunami, H. (2014) The missense of smell: functional variability in the human odorant receptor repertoire. Nat Neurosci [Epub 2013 Dec 8]. [Abstract]

Bastidas RJ, Elwell CA, Engel JN, Valdivia RH. Chlamydial intracellular survival strategies.Cold Spring Harb Perspect Med. 2013 May 1;3(5):a010256. doi: 10.1101/cshperspect.a010256. Review. PMID:  23637308 [Epub]

Barker JR, Koestler BJ, Carpenter VK, Burdette DL, Waters CM, Vance RE, Valdivia RH. STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection. MBio. 2013 Apr 30;4(3):e00018-13. doi: 10.1128/mBio.00018-13. PMID: 23631912. Free PMC Article [Epub]

Mitchel K, Lehner K. and Jinks-Robertson S.  Heteroduplex DNA position defines the roles of the Sgs1, Srs2 and Mph1 helicases in promoting distinct recombination outcomes.  PLoS Genet. 9, e1003340. 2013. [Epub]

Aksenova, A.Y., Greenwell, P. W., Dominska, M., Shishkin, A. A., Kim, J. C., Petes, T. D., and Mirkin, S. M. (2013) Genomerearrangements caused by interstitial telomeric sequences in yeast. Proc Nat Acad Sci, U S A, 110:19866-19871. [Abstract]

Haldar, A.K., Saka, H.A., Piro, A.S., Dunn, .JD., Henry, S.C., Taylor, G.A., Frickel, E.M., Valdivia, R.H., and Coers, J. (2013) IRG and GBP host resistance factors target aberrant, “non-self” vacuoles characterized by the missing of “self” IRGM proteins. PLOS Pathogens, 6:e1003414. [Abstract]

Ni, M.*, Feretzaki, M.*, Li, W., Floyd-Averette, A., Mieczkowski, P., Dietrich, F.S., and Heitman, J. (2013) Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans, PLOS Biology, 11: e1001653. [Abstract]

Nguyen BD, Valdivia RH. Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1263-8. doi: 10.1073/pnas.1117884109. Epub 2012 Jan 9.PMID:  22232666 [Epub]

Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TTH, Vary JC, Hawn TR, Dunstan SJ, Farrar JJ, Thwaites GE, King M-C, Serhan CN, Ramakrishnan L. Genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 148: 434-446. 2012. [Epub]

Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Kang D, Hafner M, Nusbaum JD, Feederle R, Delecluse HJ, Luftig MA, Tuschl T, Ohler, Uwe, and Cullen BR. The viral and cellular microRNA targetome in lymphoblastoid cell lines. PLoS Pathogens, 8: e1002484. 2012. [Epub]

Adipietro, K.A., Mainland, J.D. and Matsunami, H. (2012) Functional evolution of mammalian odorant receptors. PloS Genetics 8,:e1002821. [Abstract]

Maloney, K.A., Sullivan, L.L., Matheny, J.E., Strome, E.D., Merrett, S.L., Ferris, A., Sullivan, B.A. (2012) Functional epialleles at an endogenous human centromere. Proc Natl Acad Sci U S A, 109(34):13704-13709. [Abstract]

Mukherjee N, Corcoran DL, Nusbaum J, Reid D, Georgiev S, Hafner M, Ascano Jr., M, Tuschl T, Ohler U. and Keene JD. Integrative regulatory mapping indicates that RNA-binding protein HuR (ELAVL1) couples pre-mRNA splicing and mRNA stability. Molecular Cell 43: 327-339. 2011. [Epub]

Gottwein E, Corcoran DL, Mukherjee N, Skalsky RL, Hafner M, Nusbaum JD, Shamulailatpam P, Love CL, Dave SS, Tuschl T, Ohler U and Cullen BR. Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. Cell Host & Microbe, 10, 515-526. 2011. [Epub]

Lippert MJ, Kim N, Cho JE, Larson RP, Schoenly NE, O’Shea SH. and Jinks-Robertson S.  Role for topoisomerase 1 in transcription-associated mutagenesis in yeast.  Proc. Natl. Acad. Sci. USA 108, 698-703. 2011. [Epub]

Dey, S. and Matsunami, H. (2011). Calreticulin chaperones regulate functional expression of V2R pheromone receptors. Proc Natl Acad Sci U S A, 108:16651-16656. (Direct submission) [Abstract]

Li, Y.R., and Matsunami, H. (2011). Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling. Sci Signal 4, ra1. [Abstract]

Kim, N., Huang, S.Y., Williams, J.S., Li, Y.C., Clark, A.B., Cho, J.E., Kunkel, T.A., Pommier, Y., and Jinks-Robertson, S. (2011) Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I. Science, 332:1561-1564. [Abstract]

Li, C.H., Cervantes, M., Springer, D.J., Boekhout, T., Ruiz-Vazquez, R.M., Torres-Martinez, S.R., Heitman, J., and Lee, S.C. (2011) Sporangiospore Size Dimorphism Is Linked to Virulence of Mucor circinelloides. PLoS Pathogens, 7, e1002086. [Abstract]

Chi, J.T., Thrall, D.E., Jiang, C., Snyder, S., Fels, D., Landon, C., McCall, L., Lan, L., Hauck, M., MacFall, J.R., Vigilanti, B.L., and Dewhirst, M.W. (2011).Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics. Clinical Cancer Research 17, 2549-2560. [Abstract]

Sun, J., Singh, V., Kajino-Sakamoto, R., and Aballay, A. (2011) Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Science 332, 729-732. [Abstract]

Goldstein, D.B. (2011).The importance of synthetic associations will only be resolved empirically. PLoS Biology 18, e1001008. [Abstract]

Tang, W., Dominska, M., Greenwell, P.W., Harvanek, Z., Lobachev, K.S., Kim, H.M., Narayanan, V., Mirkin, S.M., and Petes, T.D. (2011) Friedreich’s ataxia (GAA)n•(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae. PLoS Genetics 13, e1001270. [Abstract]

Bogerd HP, Karnowski HW, Cai X, Shin J, Pohlers M and Cullen BR. A mammalian herpesvirus uses non-canonical expression and processing mechanisms to generate viral microRNAs. Molecular Cell, 37, 135-142. 2010. [Epub]

Cullen, B.R. (2010).Five questions about viruses and microRNAs. PLoS Pathogens 6, e1000787. [Abstract]

Mitchel, K., Zhang, H. Welz-Voegele, C., and Jinks-Robertson, S. (2010). Molecular structures of crossover and noncrossover intermediates during gap repair in yeast: implications for recombination. Molecular Cell 38, 211-222. [Abstract]

Stimpson, K.M., Son,g I.Y., Jauch, A., Holtgreve-Grez, H., Hayden, K.E., Bridger, J.M., and Sullivan, B.A. (2010) Telomere disruption results in non-random formation ofde novo dicentric chromosomes involving acrocentric human chromosomes. PLOS Genet, 6:e1001061. [Abstract]

Nikitin, P.A., Yan, C.M., Forte, E., Bocedi, A., Tourigny, J.P., White, R.E., Allday, M.J., Patel, A., Dave, S.S., Kim, W., Hu, K., Guo, J., Tainter, D., Rusyn, E., and Luftig, M.A. (2010) An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. Cell Host Microbe 16, 510-522.

Pickup, D.J. (2010) Propelling progeny. Science 327, 787-788. [Abstract]

Lee, P.S. and Petes, T.D. (2010) From the Cover: mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events. PNAS 107, 7383-7388. [Abstract]

Zhuang, H., Chien, M.S., and  Matsunami, H. (2009). Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates. Proc Natl Acad Sci U S A 106, 21247-21251. (Direct submission). [Abstract]

Saito, H., Chi, Q., Zhuang, H., Matsunami, H., and Mainland, J.D. (2009). Odor coding by a Mammalian receptor repertoire. Sci Signal 2, ra9. [Abstract]

Kim, N. and Jinks-Robertson, S. (2009). dUTP incorportation into genomic DNA is linked to transcription in yeast. Nature 459, 1150-1153. [Abstract]

Wheeler, F.C., Tang, H., Marks, O.A., Hadnott, T.N., Chu, P.L., Mao, L., Rockman, H.A., and Marchuk, D.A. (2009) Tnni3k modifies disease progression in murine models of cardiomyopathy. PLoS Genetics 5, e1000647. [Abstract]

Bastidas, R.J., Heitman, J., and Cardenas, M.E. (2009). The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. PLoS Pathogens 5, e1000294. [Abstract]

Whitehead, K.J., Chan, A.C., Navankasattusas, S., Koh, W., London, N.R., Ling, J., Mayo, A.H., Drakos, S.G., Jones, C.A., Zhu, W., Marchuk, D.A., Davis, G.E., and Li, D.Y. (2009). The cerebral cavernous malformation signaling pathway promotes vascular inegrity via Rho GTPases. Nature Medicine 15, 177-183. [Abstract]

Mukherjee, N., Lager, P.J., Friedersdorf, M.B., Thompson, M.A., and Keene, J.D. (2009). Coordinated post-transcriptional mRNA population dynamics during T-cell activation. Molecular Systems Biology 5, 288-302. [Abstract]

Spaeth, K.E., Chen, Y.-S., and Valdivia, R.H. (2009). TheChlamydia type III secretion system C-ring engages a chaperone-effector protein complex. PLoS Pathogens 5, e10000579. [Abstract]

Kavanaugh, L.A. and Dietrich, F.S. (2009). Non-coding RNA prediction and verification in Saccharomyces cerevisiae. PLoS Genetics 5, e1000321. [Abstract]

Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM and Cullen BR. MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature, 454, 780-783. 2008. [Epub]

Puria, R., Zurita-Martinez, S.A., and Cardenas, M.E. (2008). Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae. PNAS 105, 7194-7199. [Abstract]

Tenor, J.L. and Aballay, A. (2008). A conserved toll-like receptor is required for Caenorhabditis elegans innate immunity. EMBO reports 9, 103-109. [Abstract]

Haskins, K.A., Russell, J.F., Gaddis, N., Dressman, H.K., and Aballay, A. (2008). Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Developmental Cell 15, 87-97. [Abstract]

Kumar, Y. and Valdivia, R.H. (2008). Actin and intermediate filaments stabilize the Chlamydia trachomatis vacuole by forming dynamic structural scaffolds. Cell Host & Microbe 4, 159-169. [Abstract]

Styer, K.L., Singh, V., Macosko, E., Steele, S.E., Bargmann, C.I., and Aballay, A. (2008). Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Science 322, 460-464. [Abstract]

Idnurm, A., Walton, F.J., Floyd, A., and Heitman, J. (2008). Identification of the sex genes in an early diverged fungus. Nature 451, 193-196. [Abstract]

Cocchiaro, J.L., Kumar, Y., Fischer, E.R., Hackstadt, T., and Valdivia, R.H. (2008). Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatisparasitophorous vacuole. PNAS 105, 9379-9384. [Abstract]

Coers, J., Bernstein-Hanley, I., Grotsky, D., Parvanova, I., Howard, J.C., Taylor, G.A., Dietrich, W.F., and Starnbach, M.N. (2008). Chlamydia muridarum evades growth restriction by the IFN-{gamma}-inducible host resistance factor Irgb10. The Journal of Immunology 180, 6237-6245. [Abstract]

Keller, A., Zhuang, H., Chi, Q., Vosshall, L. B., and Matsunami, H. (2007). Genetic variation in a human odorant receptor alters odour perception. Nature, 2007 449, 468-472. [Abstract]

Ishimaru, Y., Inada, H., Kubota, M., Zhuang, H., Tominaga, M., and  Matsunami, H. (2006). Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. Proc Natl Acad Sci U S A 103, 12569-12574. (Direct submission) [Abstract]

Singh, V. and Aballay, A. (2006). Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity. PNAS 103, 13092-13097. [Abstract]

Kavanaugh, L.A., Fraser, J.A., and Dietrich, F.S. (2006). Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment. Molecular Biology and Evolution 23, 1879-1890. [Abstract]

Narayanan, V., Mieczkowski, P.A., Kim, H.M., Petes, T.D., and Lobachev, K.S. (2006). The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. Cell 125, 1283-1296. [Abstract]

Lam, A.L., Boivin, C.D., Bonney, C.F., Rudd, M.K., and Sullivan, B.A. (2006). Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. PNAS 103, 4186-4191. [Abstract]

Fraser, J.A., Giles, S.S., Wenink, E.C., Geunes-Boyer, S.G., Wright, J.R., Diezmann, S., Allen, A., Stajich, J.E., Dietrich, F.S., Perfect, J.R., and Heitman, J. (2005). Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. Nature 437, 1360-1364. [Abstract]

Lin, X., Hull, C.M., and Heitman, J. (2005). Sexual reproduction between partners of the same mating type in Cryptococcus neoformans. Nature 434, 1017-1021. [Abstract]

Lemoine, F.J., Degtyareva, N.P., Lobachev, K., and Petes, T.D. (2005). Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. Cell 120, 587-598. [Abstract]

Hall, C., Brachat, S., and Dietrich, F.S. (2005). Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryotic Cell 4, 1102-1115. [Abstract]

Idnurm, A. and Heitman, J. (2005). Light controls growth and development via a conserved pathway in the fungal kingdom. PLoS Biology 3, e95. [Abstract]

Carrel, L., and Willard, H.F. (2005). X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434, 400-404. [Abstract]

Saito, H., Kubota, M., Roberts, R. W., Chi, Q., and Matsunami, H. (2004) RTP family members induce functional expression of mammalian odorant receptors.Cell 119, 679-691. [Abstract]

Fraser, J.A., Diezmann, S. Subaran, R.L., Allen, A., Lengeler, K.B., Dietrich, F.S., and Heitman, J. (2004). Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. PLoS Biology 2, e384. [Abstract]

Sullivan, B.A. and Karpen, G.H. (2004). Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin.Nature Structural & Molecular Biology 11, 1076-1083. [Abstract]

Dobbs-McAulitte, B., Zhao, Q., Linney, E. (2004). Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo. Mechanisms of Development 121, 339-350. [Abstract]

Dietrich, F.S., Voegeli, S., Brachat, S., Lerch, A., Gates, K., Steiner, S., Mohr, C., Pohlmann, R., Luedi, P., Choi, S., Wing, R.A., Flavier, A., Gaffney, T.D., and Philippsen, P. (2004). The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome.Science 304, 304-311. [Abstract]

Udvadia, A.J. and Linney, E. (2003). Windows into development: Historic, current, and future perspectives on transgenic zebrafish. Developmental Biology, 256, 1-17. [Abstract]

Keene, J.D. and Tenenbaum, S.A. (2002). Eukaryotic mRNPs may represent posttranscriptional operons. Molecular Cell 9, 1161-1167. [Abstract]

Perz-Edwards, A., Hardison, N.L., and Linney, E. (2001). Retinoic acid-mediated gene expression in transgenic reporter zebrafish. Developmental Biology 229, 89-101. [Abstract]

Tenenbaum SA, Carson CC, Lager P. and Keene JD. Identifying mRNA subsets in mRNP complexes using cDNA arrays.  Proceedings of the National Academy of Sciences USA 97: 14085-14090. 2000. [Epub]

Linney, E., Hardison, N.L., Lonze, B.E., Lyons, S., and DiNapoli, L. (1999). Transgene expression in zebrafish: A comparison of retroviral-vector and DNA-injection approaches. Developmental Biology 213, 207-216. [Abstract]

Cardenas, M.E., Cutler, N.S., Lorenz, M.C., Di Como, C.J., and Heitman, J. (1999). The TOR signaling cascade regulates gene expression in response to nutrients.Genes & Development 13, 3271-3279. [Abstract]

Coers, J. Monahan, C., and Roy, C.R. (1999). Modulation of phagosome biogenesis by Legionella pneumophilacreates an organelle permissive for intracellular growth. Nature Cell Biology 1, 451-453. [Abstract]

Datta A, Hendrix M, Lipsitch M. and Jinks-Robertso S.  Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic recombination in yeast.  Proc. Natl. Acad. Sci. USA 94,  9757-9762. 1997. [Epub]

Johnson, D.W., Berg, J.N., Baldwin, M.A., Gallione, C.J., Marondel, I., Yoon, S.-J., Stenzel, T.T., Speer, M., Pericak-Vance, M.A., Diamond, A., Guttmacher, A.E., Jackson, C.E., Attisano, L., Kucherlapati, R., Porteous, M.E.M., and Marchuk, D.A. (1996). Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nature Genetics 13, 189-195. [Abstract]

Willard, H.F. (1996). X chromosome inactivagtion, XIST, and pursuit of the X-inactivation center. Cell 86, 5-7. [Abstract]

Datta A. and Jinks-Robertson S.  Association of increased spontaneous mutation rates with high levels of transcription in yeast.  Science 268, 1616-1619. 1995.

Greenwell, P.W., Kronmal, S.L., Porter, S.E., Gassenhuber, J., Obermaier, B. and Petes, T.D. (1995).TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82, 823-829. [Abstract]

McAllister, K.A., Grogg, K.M., Johnson, D.W., Gallione, C.J., Baldwin, M.A., Jackson, C.E., Helmbold, E.A., Markel, D.S., McKinnon, W.C., Murrell, J., McCormick, M.K., Pericak-Vance, M.A., Heutink, P., Oostra, B.A., Haitjema, T., Westerman, C.J.J., Porteous, M.E., Guttmacher, A.E., Letarte, M., and Marchuk, D.A. (1994). Endoglin, a TGF-b binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. Nature Genetics 8, 345. [Abstract]

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