FACULTY HIGHLIGHTED PUBLICATIONS

(Listed in chronological order)

Sixt BS, Bastidas RJ, Finethy R, Baxter RM, Carpenter VK, Kroemer G, Coers J, Valdivia RH. The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs. Cell Host Microbe 2017 Jan 11;21(1):113-121. doi: 10.1016/j.chom.2016.12.002. Epub 2016 Dec 29.[EPub

Gokhale NS, Horner SM.RNA modifications go viral. PLoS Pathog. 2017 Mar 9;13(3):e1006188. doi: 10.1371/journal.ppat.1006188. eCollection 2017 Mar. No abstract available. PMID:28278189

Bisogno LS, Keene JD. RNA regulons in cancer and inflammation. Curr Opin Genet
Dev. 2017 Nov 22;48:97-103. doi: 10.1016/j.gde.2017.11.004. [Epub ahead of print]
Review. PubMed PMID: 29175729.

Bisogno LS, Keene JD. Analysis of post-transcriptional regulation during
cancer progression using a donor-derived isogenic model of tumorigenesis.
Methods. 2017 Aug 15;126:193-200. doi: 10.1016/j.ymeth.2017.05.012. Epub 2017 May
19. PubMed PMID: 28529064.

Nicholson CO, Friedersdorf M, Keene JD. Quantifying RNA binding sites
transcriptome-wide using DO-RIP-seq. RNA. 2017 Jan;23(1):32-46. Epub 2016 Oct 14.
PubMed PMID: 27742911; PubMed Central PMCID: PMC5159647.

Nicholson CO, Friedersdorf MB, Bisogno LS, Keene JD. DO-RIP-seq to quantify
RNA binding sites transcriptome-wide. Methods. 2017 Apr 15;118-119:16-23. doi:
10.1016/j.ymeth.2016.11.004. Epub 2016 Nov 10. PubMed PMID: 27840290; PubMed
Central PMCID: PMC5411286.

  1. Balenga N, Azimzadeh P, Hogue JA, Staats PN, Shi Y, Koh J, Dressman H, Olson JA Jr. Orphan Adhesion GPCR GPR64/ADGRG2 is overexpressed in parathyroid tumors and attenuates calcium-sensing receptor-mediated signaling.  J Bone Miner Res. 2017 32:654-666.  PMID 27760455

JD Silverman, A Washburne, S Mukherjee, LA David. A phylogenetic transform enhances analysis of compositional microbiota data. eLife, 10.7554/eLife.21887, Feb 2017. [link]

Heaton BE, Kennedy EM, Dumm RE, Harding AT, Sacco MT, Sachs D, Heaton NS. A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.  Cell Reports. 2017 20(7): p1503-1512.  DOI: http://dx.doi.org/10.1016/j.celrep.2017.07.060  PMID: 28813663

Heaton NS. Revisiting the concept of a cytopathic viral infection. PLoS Pathogens. 2017 13(7): e1006409. https://doi.org/10.1371/journal.ppat.1006409. PMID: 28727844

Harding AT, Heaton BE, Dumm RE, Heaton NS. Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs. mBio. 2017 June 6, Vol. 8 no.3 e00669-17 doi: 10.1128/mBio.00669-17. PMID: 28588131

Eudailey J., Dennis M., Parker M., Phillips B., Huffman T., Bay C., Hudgens M., Wiseman R., Pollara J., Fouda G.G., Ferrari G., Pickup D., Kozlowski P., Van Rompay K., De Paris K., and Permar S. Maternal HIV-1 Env vaccination for systemic and breast milk immunity to prevent oral SHIV acquisition in infant macaques (2017) In press, mSphere.

Phillips B., Fouda G.G., Eudailey J., Pollara J., Curtis A.D. 2nd, Kunz E., Dennis M.,
Shen X., Bay C., Hudgens M., Pickup D., Alam S.M., Ardeshir A., Kozlowski P.A., Van Rompay
K.K.A., Ferrari G., Moody M.A., Permar S., De Paris K. (2017) Impact of Poxvirus Vector
Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120
Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques. Clin. Vaccine
Immunol. 2017 Oct 5;24(10). pii: e00231-17. doi: 10.1128/CVI.00231-17. PMCID: PMC5629672.

Sloan R, Huang SN, Pommier Y, Jinks-Robertson S.Effects of camptothecin or TOP1 overexpression on genetic stability in Saccharomyces cerevisiae. DNA Repair (Amst). 2017 Nov;59:69-75. doi: 10.1016/j.dnarep.2017.09.004. Epub 2017 Sep 18.

Guo X, Hum YF, Lehner K, Jinks-Robertson S.Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast. Mol Cell. 2017 Aug 17;67(4):539-549.e4. doi: 10.1016/j.molcel.2017.07.009. Epub 2017 Aug 3. PMID:

Hum YF, Jinks-Robertson S.Mitotic Gene Conversion Tracts Associated with Repair of a Defined Double-Strand Break in Saccharomyces cerevisiae. Genetics. 2017 Sep;207(1):115-128. doi: 10.1534/genetics.117.300057. Epub 2017 Jul 25. PMID:

Kim N, Jinks-Robertson S.The Top1 paradox: Friend and foe of the eukaryotic genome.
DNA Repair (Amst). 2017 Aug;56:33-41. doi: 10.1016/j.dnarep.2017.06.005. Epub 2017 Jun 9. Review.
PMID:

Cho JE, Jinks-Robertson S.Ribonucleotides and Transcription-Associated Mutagenesis in Yeast.
J Mol Biol. 2017 Oct 27;429(21):3156-3167. doi: 10.1016/j.jmb.2016.08.005. Epub 2016 Aug 7. Review. PMID:

Larsen PA*, Harris RA*, Liu Y, Murali SC, Campbell CR, Brown AD, Sullivan BA, Shelton J, Brown SJ, Raveendran M, Dudchencko O, Machol I, Lieberman E, Muzny DM, Gibbs RA, Yoder AD, Rogers J, Worley KC (2017) Hybrid de novo assembly and centromere characterization of the gray mouse lemur (Microcebus murinus). BMC Biology, 15:110. (*joint first authors) https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0439-6

McNulty SM, Sullivan LL, Sullivan BA (2017) Human centromeres produce chromosome-specific and array-specific alpha satellite transcripts that are complexed with CENP-A and CENP-C. Dev Cell, 42:226-240. https://www.ncbi.nlm.nih.gov/pubmed/28787590

Johnson WL*, Yewdell WT*, Bell JC, McNulty SM, Duda Z, O’Neill RJ, Sullivan BA, Straight AF (2017) RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin. eLife, 6:e25299. (*joint first authors) https://elifesciences.org/articles/25299

McFadden MJ, Gokhale NS, Horner SM.Protect this house: cytosolic sensing of viruses. Curr Opin Virol. 2017 Feb;22:36-43. doi: 10.1016/j.coviro.2016.11.012. Epub 2016 Dec 9. Review.PMID:27951430

Gokhale NS, Horner SM.Knotty Zika Virus Blocks Exonuclease to Produce Subgenomic Flaviviral RNAs.Cell Host Microbe. 2017 Jan 11;21(1):1-2. doi: 10.1016/j.chom.2016.12.013.PMID:28081439

Vazquez C, Beachboard DC, Horner SM.Methods to Visualize MAVS Subcellular Localization.Methods Mol Biol. 2017;1656:131-142. doi: 10.1007/978-1-4939-7237-1_7.PMID:28808966

  1. Himburg HA, Sasine J, Yan X, Kan J, Dressman H, Chute JP. A molecular profile of the endothelial cell response to ionizing radiation. Radiation Research. 2016 186:141-52. PMID 27387861

Price AM, Dai J, Bazot Q, Patel L, Nikitin PA, Djavadian R, Winter PS, Salinas CA, Barry AP, Wood KC, Johannsen EC, Letai A, Allday MJ, Luftig MA. Elife. Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection. 2017 Apr 20;6. pii: e22509. doi: 10.7554/eLife.22509.

Kennedy, Edward M., Bogerd, Hal P., Kornepati, Anand V.R., Kang, Dong, Ghoshal, Delta, Marshall, Joy B., Poling, Brigid C., Tsai, Kevin, Gokhale, Nandan S., Horner, Stacy M. and Cullen, Bryan R. (2016). Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Cell Host and Microbe, 19: 675-685

Kennedy, Edward M. and Cullen, Bryan R. (2017) Gene Editing: A New Tool for Viral Disease. Annual Review of Medicine, 68: 401-411.

Kennedy, Edward M., Kornepati, Anand V., Bogerd, Hal P. and Cullen, Bryan R. (2017) Partial reconstitution of the RNAi response in human cells using Drosophila gene products. RNA, 23: 153-160.

Bogerd, Hal P., Kennedy, Edward M., Whisnant, Adam W. and Cullen, Bryan R. (2017) Induced packaging of cellular microRNAs into HIV-1 virions can inhibit infectivity. mBio, 8: e02125-16.

Kennedy, Edward M., Courtney, David G., Tsai, Kevin and Cullen, Bryan R. (2017) Viral epitranscriptomics. Journal of Virology, 91: e02263-16.

Poling, Brigid C., Tsai, Kevin, Kang, Dong, Ren, Linda, Kennedy, Edward M. and Cullen, Bryan R. (2017) A lentiviral vector bearing a reverse intron demonstrates superior expression of both proteins and microRNAs. RNA Biology. 1-10. doi:10.1080/15476286.2017.1334755.

Courtney, David G., Kennedy, Edward M., Dumm, Rebekah E., Bogerd, Hal P., Tsai, Kevin, Heaton, Nicholas S. and Cullen, Bryan R. (2017) Epitranscriptomic enhancement of influenza A virus gene expression and replication. Cell Host & Microbe, 22: 377-386.e5.

Cullen, Bryan R. (2017) RNA interference in mammals: The virus strikes back. Immunity, 46: 970-972.

Poling, Brigid C., Price, Alexander M., Luftig, Micah A. and Cullen, Bryan R. (2017). The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cis. Virology, 512: 113-123.

Heaton, Nicholas S. and Cullen, Bryan R. (2017). Viruses hijack a long noncoding RNA. Nature, in press

Piro, AS., Hernandez, D., Luoma, S., Feeley, EM., Finethy, R., Yirga, A., Frickel, EM., Lesser, CF., Coers, J. Detection of cytosolic Shigelle flexneri via a C-terminal triple-ariginine motif of GBP1 inhibits actin-based motility. mBio 2017 Dec 12;8(6) pii: e01979-17. PMID: 29233899

Feeley, EM.*, Pilla-Moffett, D.*, Zwack, EE., Piro, AS., Finethy, R., Kolb, JP, Martinez, J., Brodsky, IE., Coers, J. Galectin-3 directs antimicrobial Guanylate Binding Proteins to vacuoles furnished with bacterial secretion systems. (*Authors contributed equally to this study). Proc Natl Acad Sci U.S.A. 2017 Feb 28;114(9):E1698-E1706 PMID: 28193861

Finethy, R., Luoma, S., Orench-Rivera, N., Feeley, EM., Haldar, AK., Yamaoto, Y., Kanneganti, TD., Kuehn, MJ., Coers, J. Inflammasome activation by bacterial outer membrane vesicles requires guanylate binding proteins. mBio 2017 Oct 3;8(5). pii: e01188-17. PMID: 28974614

Zhang K, Xue-Chang W, Zheng D-Q, Petes TD Effects of temperature on the meiotic recombination landscape of the yeast Saccharomyces cerevisiae. mBio 2017, in press.

McGinty RJ, Rubinstein RG, Neil AJ, Dominska M, Kiktev D, Petes TD, Mirkin SM. Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair. Genome Res. 2017 Nov 7. doi: 10.1101/gr.228148.117. PMID: 29113982 [EPub]

Yin Y, Dominska M, Yim E, Petes TD. High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast. Elife. 2017 Jul 17;6. pii: e28069. doi: 10.7554/eLife.28069. PMID: 28714850 [EPub]

Zhao Y, Dominska M, Petrova A, Bagshaw H, Kokoska RJ, Petes TD. Properties of Mitotic and Meiotic Recombination in the Tandemly-Repeated CUP1 Gene Cluster in the Yeast Saccharomyces cerevisiae. Genetics. 2017 Jun;206(2):785-800. doi: 10.1534/genetics.117.201285. Epub 2017 Apr 4. PMID: 28381587 [EPub]

Lennox, AL, Mao, H, and Silver, DL. RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development. Wiley Interdisciplinary Reviews Developmental Biology. Aug 24 online. 2017 Invited review article.[EPub]

Feb Letters cover Pilaz, L-J. and Silver, DL. Moving messages in the developing brain: Emerging roles for mRNA transport and local translation in neural stem cells. FEBs Letters. June; 591 (11): 1526-2539. 2017 Invited review article.[EPub]

 

 

Miller, EE+, Kobayashi, GS+, Musso, CM, Allen, M, Ishiy, FAA, Caires Junior, LC, Guimarães, ESG, Griesi-Oliveira, K, Zechi-Ceide, RM, Richieri-Costa, A, Bertola, DR, Passos-Bueno, MR*, Silver, DL*. EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira Syndrome. Human Molecular Genetics. June 15; 26 (12): 2177-2191. 2017, *co-corresponding authors, + co-first authors [EPub]

Mao, H, Brown, H, and Silver, DL. Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex. RNA. Jan;23(1):23-31. 2017[EPub]

Carpenter V1, Chen YS1, Dolat L1, Valdivia RH1.The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles. mSphere. 2017 Jul 19;2(4). pii: e00207-17. doi: 10.1128/mSphere.00207-17. eCollection 2017 Jul-Aug.[EPub]

Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS. Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell. 2017 Oct 5;171(2):481-494. PMID: 28985567.[EPub]

Subramanian S, Gottschalk WK, Kim SY, Roses AD, Chiba-Falek O. The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster. Biochim Biophys Acta. 2017 Mar;1863(3):810-816. PMID: 28065845.[EPub]

Davison, J.M., Lickwar, C.R., Song, L., Breton, G., Crawford, G.E., and Rawls, J.F. (2017) Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha. Genome Research 27(7): 1195-1206. [EPub] [News Release]

Lickwar, C.R., Camp, J.G., Weiser, M., Kingsley, D.M., Furey, T.S., Sheikh, S.Z., and Rawls, J.F. (2017) Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells. PLoS Biology 15(8):e2002054 [EPub] [News Release]

McClung JM, McCord TJ, Ryan TE, Schmidt CA, Green TD, Southerland KW, Reinardy JL, Mueller SB, Venkatraman TN, Lascola CD, Keum S, Marchuk DA, Spangenburg EE, Dokun A, Annex BH, Kontos CD. BAG3 (Bcl-2-Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy.Circulation. 2017 Jul 18;136(3):281-296. doi: 10.1161/CIRCULATIONAHA.116.024873. Epub 2017 Apr 25. [EPub]

Billmyre RB, Clancey SA, Heitman J. Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii. eLife. 2017 Sep 26;6. pii: e28802. doi: 10.7554/eLife.28802.[EPub]

Sun S, Yadav V, Billmyre RB, Cuomo CA, Nowrousian M, Wang L, Souciet JL, Boekhout T, Porcel B, Wincker P, Granek JA, Sanyal K, Heitman J. Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination. PLoS Biol. 2017 Aug 11;15(8):e2002527. doi: 10.1371/journal.pbio.2002527. eCollection 2017 Aug.[EPub]

Chow EW, Clancey SA, Billmyre RB, Averette AF, Granek JA, Mieczkowski P, Cardenas ME, Heitman J. Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans. PLoS Genet. 2017 Apr 4;13(4):e1006667. doi: 10.1371/journal.pgen.1006667. eCollection 2017 Apr. [EPub]

Calo S, Nicolás FE, Lee SC, Vila A, Cervantes M, Torres-Martinez S, Ruiz-Vazquez RM, Cardenas ME, Heitman J. A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides. PLoS Genet. 2017 Mar 24;13(3):e1006686. doi: 10.1371/journal.pgen.1006686. eCollection 2017 Mar. [EPub]

 Sharma R, Ishimaru Y, Davison I, Ikegami K, Chien MS, You H, Chi Q, Kubota M, Yohda M, Ehlers M, Matsunami H.Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice.Elife. 2017 Mar 6;6. pii: e21895. doi: 10.7554/eLife.21895.[EPub]

Pilaz, L-J, Lennox, A.L., Rouanet, J.P., and Silver, DL. Dynamic mRNA transport and local translation in radial glial progenitors of the developing brain. Current Biology. Dec 19;26(24):3383-3392. 2016 (Featured in accompanying Preview article in same issue by Ehses et al. and in F1000Prime).[EPub]

Haldar, AK., Piro, AS., Finethy, R., Espenschied, ST., Brown, HE., Giebel, AM., Frickel, E-A., Nelson, DE., Coers, J. Chlamydia trachomatis is resistant to inclusion ubiquitination and associated host defense in IFNgamma-primed human cells. mBio 2016. Dec 13;7(6). pii: e01417-16. PMID: 27965446

Aldrup-MacDonald ME*, Kuo ME*, Sullivan LL*, Chew K, Sullivan BA (2016) Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles. Genome Res 26:1301-1311. (*joint first authors)
http://genome.cshlp.org/content/26/10/1301.full
press release: https://www.eurekalert.org/pub_releases/2016-08/du-vi083016.php
radio spot: http://www.wfdd.org/story/predictive-power-junk-your-genome-0.

Ross JE, Woodlief KS, Sullivan BA (2016) Inheritance of the CENP-A chromatin domain is spatially and temporally constrained at human centromeres. Epigenetics Chromatin 9:20.
https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-016-0071-7

Smola MJ, Christy TW, Inoue K, Nicholson CO, Friedersdorf M, Keene JD, Lee DM,
Calabrese JM, Weeks KM. SHAPE reveals transcript-wide interactions, complex
structural domains, and protein interactions across the Xist lncRNA in living
cells. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10322-7. doi:
10.1073/pnas.1600008113. Epub 2016 Aug 30. PubMed PMID: 27578869; PubMed Central
PMCID: PMC5027438.

Wetzel-Strong SE, Detter MR, Marchuk DA. The pathobiology of vascular malformations: insights from human and model organism genetics. J Pathol. 2017 Jan;241(2):281-293. doi: 10.1002/path.4844. Epub 2016 Dec 4. Review. PMID: 27859310 [EPub]

Roko-Rasin, M, and Silver, D. The crossroads of RNA regulation and function in neurodevelopment. Int J Dev Neurosci. Dec;55:101. 2016. Invited review article.[EPub]

McMahon, JJ, Miller, EE, and Silver, DL. The exon junction complex in neural development and neurodevelopmental disease. International Journal of Developmental Neuroscience. 2016 Dec;55:117-123. 2016 Invited review article.[EPub]

Mao, H, McMahon, JJ, Tsai, Y-H., Wang, Z, and Silver, DL. Haploinsufficiency for core exon junction complex components disrupts neurogenesis and causes p53-mediated microcephaly. PLoS Genetics. Sept. 12.; 12(9): e1006282. 2016 (Featured in radio interview)[EPub]

Silver, DL. Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex. Bioessays. Feb;38(2)162-71. 2016 Invited review article.[Abstract]

Zheng DQ, Zhang K, Wu XC, Mieczkowski PA, Petes TD. Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8114-E8121. Epub 2016 Nov 28. PMID: 27911848 [EPub]

Singh, SK, Stogsdill, JA, Pulimood, N, Dingsdale, H, Kim YH, Pilaz, LJ, Kim, IH, Manhaes, AC, Rodrigues-Junior, WS, Pamukcu, A, Enustun, E, Ertuz, Z, Scheiffele, P, Soderling, S, Silver, DL, Li, R, Medina, AJ, and Eroglu, C. Astrocytes Assemble Thalamocortical Synapses by Bridging Neurexin-1α and Neuroligin-1 via Hevin. Cell. Jan 14; 164 (1-2): 183-96. 2016 [EPub]

Pilaz, LJ, McMahon, JJ, Miller, EE, Lennox, AL, Suzuki, A, Salmon, E, Silver, DL, Prolonged mitosis of neural progenitors alters cell fate in the developing brain. Neuron. Jan 6; 89(1):83-99. 2016 (Featured in F1000Prime).[EPub]

Cronan MR1, Beerman RW1, Rosenberg AF1, Saelens JW1, Johnson MG2, Oehlers SH1, Sisk DM1, Jurcic Smith KL3, Medvitz NA4, Miller SE4, Trinh LA5, Fraser SE5, Madden JF4, Turner J6, Stout JE2, Lee S3, Tobin DM7.Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection.Immunity. 2016 Oct 18;45(4):861-876. doi: 10.1016/j.immuni.2016.09.014. [EPub]

Andersen SL, Zhang A, Dominska M, Moriel-Carretero M, Herrera-Moyano E, Aguilera A, Petes TD. High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast. PLoS Genet. 2016 Mar 11;12(3):e1005938. doi: 10.1371/journal.pgen.1005938. eCollection 2016 Mar.PMID: 26968037 [EPub]

Feretzaki M, Billmyre RB, Clancey SA, Wang X, Heitman Gene Network Polymorphism Illuminates Loss and Retention of Novel RNAiSilencing Componenets in the Cryptococcus Pathogenic Species Complex.  J.PLoS Genet. 2016 Mar 4 12(3):e1005868. doi: 10.1371/journal.pgen.1005868. eCollection 2016 Mar. [EPub]

Shi C, Shenkar R, Zeineddine HA, Girard R, Fam MD, Austin C, Moore T, Lightle R, Zhang L, Wu M, Cao Y, Gunel M, Louvi A, Rorrer A, Gallione C, Marchuk DA, Awad IA. B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models.J Neuroimmune Pharmacol. 2016 Jun;11(2):369-77. doi: 10.1007/s11481-016-9670-0. Epub 2016 Apr 16. PMID: 27086141
[EPub]

Sullivan LL, Maloney KA, Towers AJ, Gregory SG, Sullivan BA (2016) Human centromere repositioning within euchromatin after partial chromosome deletion. Chromosome Res 24(4):451-466.
http://www.readcube.com/articles/10.1007/s10577-016-9536-6

Girard R, Zeineddine HA, Orsbon C, Tan H, Moore T, Hobson N, Shenkar R, Lightle R, Shi C, Fam MD, Cao Y, Shen L, Neander AI, Rorrer A, Gallione C, Tang AT, Kahn ML, Marchuk DA, Luo ZX, Awad IA. Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease. J Neurosci Methods. 2016 Sep 15;271:14-24. doi: 10.1016/j.jneumeth.2016.06.021. Epub 2016 Jun 23. PMID: 27345427 [EPub]

 Bae S, Mueller O, Wong S, Rawls JF, Valdivia RH

Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe.Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):14127-14132. Epub 2016 Nov 23. [EPub]

Zhou T, Chien MS, Kaleem S, Matsunami H Single cell transcriptome analysis of mouse carotid body glomus cells.J Physiol. 2016 Aug 1;594(15):4225-51. doi: 10.1113/JP271936. Epub 2016 Apr 13.[EPub]

McFadden K, Hafez AY, Kishton R, Messinger JE, Nikitin PA, Rathmell JC, Luftig MA (2016) Metabolic stress is a barrier to Epstein-Barr virus mediated B-cell immortalization. Proc Natl Acad Sci U S A 113:E782-90. [Article]

Meng L, Mulcahy B, Cook SJ, Neubauer M, Wan A, Jin Y, Yan D. The cell death pathway regulates synapse elimination through cleavage of celsolin in Caenorhabditis elegans neurons. Cell Rep, 11:1737-48.  2015. PMCID: PMC4481169. [EPub]

Haldar, AK., Finethy, R., Piro, AS., Feeley, EM., Pilla-Moffett, D., Foltz, C., Komatsu, M., Frickel, EM., Coers, J. Ubiquitin systems mark pathogen-containing vacuoles for host defense by Guanylate Binding Proteins. Proc Natl Acad Sci U.S.A. 2015 Oct 13;112(41):E5628-37. PMID: 26417105

Finethy, R., Jorgensen, I., Haldar, AK., de Zoete, MR., Flavell, RA., Yamamoto, M., Nagarajan, UM., Miao, EA., Coers, J. Guanylate Binding Proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. Infection and Immunity 2015 Dec; 83(12):4740-9. PMID: 26416908

Kang D, Skalsky RL, Cullen BR. EBV BART microRNAs target multiple pro-apoptotic cellular genes to promote epithelial cell survival. PLoS Pathogens, 11, e1004979, 2015. [Epub]

Blackinton JG, Keene JD. Functional coordination and HuR-mediated regulation
of mRNA stability during T cell activation. Nucleic Acids Res. 2016 Jan
8;44(1):426-36. doi: 10.1093/nar/gkv1066. Epub 2015 Oct 20. PubMed PMID:
26490963; PubMed Central PMCID: PMC4705648.

Jiang Y, Gong NN, Hu XS, Ni MJ, Pasi R, Matsunami H.Molecular profiling of activated olfactory neurons identifies odorant receptors for odors in vivo.Nat Neurosci. 2015 Oct;18(10):1446-54. doi: 10.1038/nn.4104. Epub 2015 Aug 31. [EPub]

Kokes M. Dunn JD, Granek JA, Nguyen BD, Barker JR, Valdivia RH, Bastidas RJ. Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia. Cell Host Microbe. 2015. [Epub]

Oehlers SH, Cronan MR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS,     Tobin DM. Interception of host angiogenic signalling limits mycobacterial growth. Nature 517: 612-15, 2015. [Epub]

Minchin_Rawls_PNAS_April 7 2015Minchin JN, Dahlman I, Harvey CJ, Mejhert N, Singh MK, Epstein JA, Arner P, Torres-Vázquez J and Rawls JF. Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in viseceral adipose tissue. Proc Natl Acad Sci USA 112(14): 4363-8. 22015, 2015. [Epub] Featured on  cover.

 

 

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