Lucas Serdar

Lucas Serdar

Contact Information:

Silver Lab

Research Interest:
I am interested in all aspects of RNA biology. During my Ph.D. work, I studied the molecular mechanisms underlying the nonsense-mediated mRNA decay (NMD) pathway in budding yeast. My research in the Silver lab maintains a focus on post-transcriptional gene regulation, and centers on understanding the regulation of mRNA localization and localized translation in radial glial cells.

Personal Interest:
In my free time I enjoy running and biking.

Publication List:

Kanagasabai, R., Serdar, L., Karmahapatra, S., Kientz, C.A., Ellis, J., Ritke, M.K., Elton, T.S. and Yalowich, J.C. Alternative RNA Processing of Topoisomerase II╬▒ in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform. J. Pharmacol. Exp. Ther360: 152-63 (2017).

Serdar, L.D.Whiteside, D.L., and Baker, K.E. ATP hydrolysis by UPF1 is required for efficient translation termination at premature stop codons. Nat. Commun. 7:14021 (2016).