Spinocerebellar ataxias are a family of neurodegenerative disorders affecting muscle coordination and control. Because the brain is such a complex organ, these disorders have been poorly understood.
MGM’s Luke Bartelt and Craig Lowe, with other colleagues, are using single-cell RNA sequencing technologies to better understand how these diseases form, which may lead to better treatment options for patients. Luke is lead author on this month’s Science Translational Medicine publication about the team’s recent results.
MGM’s Matt Scaglione reported from the 2024 International Congress for Ataxia Research that the keynote speaker, NINDS Director Walter Koroshetz, talked about the revolutionary change that is coming from single-cell techniques. Dr. Koroshetz highlighted the Science Translational Medicine paper as an important example of how these new single-cell technologies can allow us to better understand human diseases and disorders.
To read more about the Duke team’s recent research, click here.