Joklik Distinguished Lectureship

The Joklik Distinguished Lectureship honors and commemorates the myriad contributions of Professor Wolfgang Karl (Bill) Joklik, D.Phil. (Oxford) to the Department of Microbiology and Immunology at Duke, which he chaired for 24 years; to the institution at large, and for his role as the co-founder of the Duke Comprehensive Cancer Center. Dr. Joklik is a member of the AOA honor society, recipient of an Alexander von Humboldt Professorship, and recipient of the ICN International Prize in Virology. He is a member of the U.S. National Academy of Sciences, and the U.S. National Academy of Medicine. With this lectureship we honor his contributions to the broader community of microbiology and infectious disease, as well as for his research achievements in virology, and his founding of the American Society for Virology, as editor in chief of the journal Virology, editor of the Journal of Biological Chemistry, editor in chief of Microbiological Reviews and editor and author of the widely used medical school textbook, Zinsser Microbiology.

Wolfgang Bill Joklik_April 2013 News

A native of Austria and raised in Australia, much of Dr. Joklik’s research focused on understanding the reovirus and vaccinia poxvirus model systems; and much of his career in general was devoted to championing the field of molecular virology. As postdoctoral fellows with Herman Kalckar in Copenhagen, Bill Joklik, and now Nobel Laureate Paul Berg discovered, isolated and characterized nucleoside diphosphokinase, the enzyme that exchanges the gamma phosphate between nucleoside triphosphates and is now known to function in signal transduction pathways. In his own laboratory, Dr. Joklik made very early contributions to understanding the mechanisms of action of interferons–the first cytokines analyzed on the molecular level, subsequently leading to his election as an honorary member of the International Society for Interferon and Cytokine Research. His lab was the first to determine the mode of reovirus replication and to sequence the reovirus genes and proteins. Many outstanding alumni trained in Dr. Joklik’s laboratory notably, Sir John Skehel, Director (1987-2006) of the National Institute for Medical Research, London, and the late Bernard Fields M.D., Adele Lehman Professor and chairman of the Department of Microbiology and Molecular Genetics of Harvard Medical School, a member of the U.S. National Academy of Sciences and author of the textbook, Fields Virology.

WKJ WashDuke_Joklik_2012

Dr. Joklik enjoying lunch at the Washington Duke Inn.

David Jack Susan Bill Joklik

From L to R: Dr. David Pickup, Dr. Jack Keene, Ms. Susan Wiley, and Dr. Bill Joklik

 

 

 

 

 

 

 

Bill Joan Jack 1017_Joklik-13

Dr. Joklik, left, with world-renowned RNA biologist, Dr. Joan Steitz, middle, visiting duke from Yale and former Chair of Microbiology, Dr. Jack Keene, right.

Anylan and Joklik 7-2011

Dr. Joklik, right, with long-time colleague and friend Dr. Bill Anlyan, left, former Chancellor of Duke Medicine.

 

OLYMPUS DIGITAL CAMERA

Dr. Joklik, left, with our first Joklik Lecturer, Dr. Bernie Moss, right.

OLYMPUS DIGITAL CAMERA

Dr. Joklik and Dr. Moss chatting at the 2010 MGM Scientific Retreat.

Karla and Micah_Joklik 2011

Dr. Micah Luftig, right, congratulating our 2011 Joklik lecturer, Dr. Karla Kirkegaard, left, Chair of Microbiology at Stanford University School of Medicine.

 

 

 

 

Michael Malim_Joklik 2013

Dr. Bryan Cullen, left, with former trainee and 2013 Joklik lecturer, Dr. Michaek Malim, right.

 

 

 

 

Beatrice Hahn_Joklik 2014

Dr. Tim Haystead, Professor of Pharmacology and Cancer Biology, left, chatting with our 2014 Joklik lecturer, Dr. Beatrice Hahn (turquoise top), Dr. Bryan Cullen and Dr. Jack Keene (far right).

 

 

Lynn Enquist_Joklik 2015-Plaque

Dr. Micah Luftig, right, congratulating Dr. Lynn Enquist, our 2015 Joklik lecturer, visiting from Princeton.

Lynn Enquist and Stacy Horner_Joklik 2015

Dr. Stacy Horner, left, chatting with Dr. Lynn Enquist in 2015.

 

 

 

 

 

 

 

 

 

 

 

 

Dr. Joklik is currently a James B. Duke Professor and Chairman Emeritus of Molecular Genetics and Microbiology and an active member of the Durham community.

Wolfgang Karl Joklik-autobiography

List of Speakers

2010-Bernard Moss-Joklik poster

First Annual Lecture – September 25, 2010
“Poxviruses do it all in the cytoplasm”
Dr. Bernard Moss
National Institute of Allergy and Infectious Diseases

 

 

 

 

 

 

 

2011-Kirkegaard Joklik posterSecond Annual Lecture – September 23, 2011
“Positive-strand RNA viruses: Dominant drug targets and novel routes of viral spread”
Karla Kirkegaard, PhD
Stanford University School of Medicine

 

 

 

 

 

 

2012-Harrison Joklik Lectureship Poster

 

Third Annual Lecture – September 21, 2012
“Cell entry of non-enveloped viruses”
Stephen Harrison, PhD
Harvard Medical School

 

 

 

 

 

 

2013-Malim-Joklik LectureFourth Annual Lecture – September 7, 2013
“Exploiting replication deficiencies to illuminate HIV/host interactions”
Michael Malim, DPhil
King’s College, London School of Medicine

 

 

 

 

 

 

2014-Hahn_Joklik plaqueFifth Annual Lecture, September 6, 2014
“Origins of Human AIDS and Malaria”
Beatrice Hahn, MD
University of Pennsylvania, Perelman School of Medicine

 

 

 

 

 

 

Sixth Annual Lecture, September 12, 2015
“Axons, the front line sensors of alpha herpesvirus
PNS invasion”
Lynn Enquist
Princeton University

 

 

 

 

 

Seventh Annual Lecture, September 10, 2016
“Innate Immunity & Human Herpesviruses”
Blossom Damania, PhD
University of North Carolina, Chapel Hill

 

 

 

Eighth Annual Lecture, September 9, 2017
“Virus and host signaling of innate immune activiation”
Michael Gale, Jr., PhD
University of Washington