Jeff Bourgeois, Jr.

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UPGG Graduate Student (2016)
0049 CARL, DUMC 3053
Durham, NC 27710
Phone: 919.684.5834


I grew up in rural Glocester, RI before moving to Worcester, MA to attend the College of the Holy Cross. While at Holy Cross I performed research in Dr. Julia Paxson’s lab studying the effects of cigarette smoke on the lungs, as well as the effects of age on the ability for resident lung stem cells to repair damage caused by cigarette smoke. I also performed a summer internship at the NIH in Dr. Irini Sereti’s lab studying Idiopathic CD4 Lymphocytopenia pathogenesis and treatment.

Research Interests

At Duke, entered through UPGG and have joined the Ko lab. My research interests focus on how differential host-pathogen interactions lead to different disease outcomes, and how these interactions have shaped the evolution of both the hosts and pathogens. My current project examines how disruptions of methionine metabolic pathways alter host and pathogen biology during infection.

Personal Interests

I spend my free time listening to music, reading, playing intramural wallyball, and exploring the Durham brewery scene.


Bourgeois JS, Jacob J, Garewal A, Ndahayo R, Paxson J. 2016. The Bioavailability of Soluble Cigarette Smoke Extract Is Reduced through Interactions with Cells and Affects the Cellular Response to CSE Exposure. PLoS One 11.

Sheikh V, Porter BO, DerSimonian R, Kovacs SB, Thompson WL, Perez-Diez A, Freeman AF, Roby G, Mican J, Pau A, Rupert A, Adelsberger J, Higgins J, Bourgeois JS Jr, Jensen SM, Morcock DR, Burbelo PD, Osnos L, Maric I, Natarajan V, Croughs T, Yao MD, Estes JD, Sereti I. 2016. Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia. Blood 125, 977-88.