Liza Rassadkina

Liza Rassadkina2021 MGM Graduate Student





Research Interest: I graduated from Rutgers University in 2019 with a B.S. in Microbiology. During my time as an undergraduate I worked in Dr. Tamar Barkay’s lab where I studied extremophilic microbial communities from various hot springs in Yellowstone National Park. I focused on bacterial and archaeal growth in mercury enriched hot springs while looking for potential mercury resistance and mercury methylation. After graduating, I joined Dr. Xu Yu’s lab which studies HIV at the Ragon Institute of MGH, MIT, and Harvard. During my time there, I worked on various projects that involve looking at the HIV-1 reservoir of infected patients currently undergoing treatment. Some of my projects included looking at the reservoir of infants from Botswana and Mozambique, identifying reservoir decrease in patients enrolled in clinical drug trials, and looking at lncRNA related metabolic function of immune cells in HIV-1 elite controllers. In addition, during the pandemic I was fortunate enough to be able to help out by processing COVID blood samples and then being able to work on projects using those same samples. At Duke, I am interested in continuing to work with pathogens with a focus on host-pathogen interactions, but looking at it from the pathogen perspective. 

Personal Interests: In my free time I like swimming and visiting museums and aquariums. When the weather is nice I like to walk around and explore cities. Other than that I love reading and watching documentaries.  

Publications List (if applicable): 1Hartana CA, Rassadkina Y, Gao C, Martin-Gayo E, Walker BD, Lichterfeld M, Yu XG. Long noncoding RNA MIR4435-2HG enhances metabolic function of myeloid dendritic cells from HIV-1 elite controllers. J Clin Invest. 2021 May 3; 131(9):e146136. doi: 10.1172/JCI146136.  2Rassadkina Y, Roth S, Barkay T. Characterizing and Evaluating the Diverse Microbial Communities and Their Mercury Resistance Potential  from Hot Spring Sites Representing Gradients in Temperature and pH in Yellowstone National Park. Rutgers Undergraduate Research Journal. 2020 Dec; 1(1):1-16 3Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ; Massachusetts Consortium for Pathogen Readiness. SARS-CoV-2 viral load is associated with increased disease severity and mortality. Nat Commun. 2020 Oct 30; 11(1):5493. doi: 10.1038/s41467-020-19057-5. (Member of Massachusetts Consortium for Pathogen Readiness.) 4. Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN,  Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li J, Khatri A, Chu HY; MGH COVID-19 Collection & Processing Team, Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity. Science. 2020 Sep 29:eabd4250. doi: 10.1126/science.abd4250. (Member of MGH COVID-19 Collection & Processing Team) 5. Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC,  Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF Jr, Pillai S; Massachusetts Consortium on Pathogen Readiness Specimen Working Group. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. 2020 Oct 1; 183(1):143-157.e13. doi: 10.1016/j.cell.2020.08.025