Research Interest: My main research interest is host microbial interactions. I am interested in looking at how microbial populations behave within the host and how they adapt and respond to changing environmental conditions (ie during treatment). I am interested in exploring how best to prevent pathogen escape and rebound during treatment, as well as investigating how the host immune system can influence a bacteria or virus on a molecular level. Past research includes investigating population changes in HIV, studying bacterial biofilms, and investigating bacteriophage/antibiotic combinations.
Personal Interests: Traveling everywhere, watching football (Go Patriots!), reading, eating cheesy foods, hiking, spending time with friends, cooking, and playing with dogs.
Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound
Cale EM, Bai H, Bose M, Messina MA, Colby DJ, Sanders-Buell E, Dearlove B, Li Y, Engeman E, Silas D, O’Sullivan AM, Mann B, Pinyakorn S, Intasan J, Benjapornpong K, Sacdalan C, Kroon E, Phanuphak N, Gramzinski R, Vasan S, Robb ML, Michael NL, Lynch RM, Bailer RT, Pagliuzza A, Chomont N, Pegu A, Doria-Rose NA, Trautmann L, Crowell TA, Mascola JR, Ananworanich J, Tovanabutra S, Rolland M, on behalf of the RV397 Study Group. 2020. Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound. J Clin Invest 130.