Dia Beachboard, PhD
0049 CARL Bldg
Box 3053 DUMC
Durham, NC 27710
Phone: (919) 684-2319
Fax: (919) 613-8646
Research Interest: Virus-host interaction, antiviral innate immunity
I received my B.S. in Microbiology form the University of Tennessee in 2006. I worked in the laboratory of Pamela Small identifying the environmental reservoir of Mycobacterium ulcerans before I decided to go to graduate school. I attended Vanderbilt University for graduate school, under the mentorship of Mark Denison. In 2015, I received my Ph.D. in Microbiology and Immunology characterizing the role of a viral non-structural protein in virus induced membrane modifications and viral fitness. My interest in virus-host interaction and antiviral innate immunity lead me to Stacy Horner’s lab in March 2015. My work focuses on regulation of the antiviral innate immune response to Hepatitis C virus.
Personal Interests: Outside of the lab, I enjoy crocheting, reading, playing board games, and hiking.
Beachboard DC, Anderson-Daniels JM, Denison MR. 2015. Mutations across Murine Hepatitis Virus nsp4 Alter Virus Fitness and Membrane Modifications. J Virol 89:2080–2089.
Beachboard, D. C., X. Lu, S. C. Baker, and M. R. Denison. 2013. Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive. Virology 435:210-213.
Oswald-Richter, K. A., D. C. Beachboard, E. H. Seeley, S. Abraham, B. E. Shepherd, C. A. Jenkins, D. A. Culver, R. M. Caprioli, and W. P. Drake. 2012. Dual Analysis for Mycobacteria and Propionibacteria in Sarcoidosis BAL. Journal of clinical immunology 32:1129-1140.
Oswald-Richter, K.A., Beachboard, D.C., Zhan, X., Gaskill, C.F., Abraham, S., Jenkins, C., Culver, D.A., and Drake, W. (2010). Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis. Respir Res 11, 161.
Gadlage, M.J., Sparks, J.S., Beachboard, D.C., Cox, R.G., Doyle, J.D., Stobart, C.C., and Denison, M.R. (2010). Murine hepatitis virus nonstructural protein 4 regulates virus-induced membrane modifications and replication complex function. J Virol 84, 280-290.
Aubry, S., Lee, R.E., Mahrous, E.A., Small, P.L., Beachboard, D., and Kishi, Y. (2008). Synthesis and structure of mycolactone E isolated from frog mycobacterium. Org Lett 10, 5385-5388.
Williamson HR, Benbow ME, Nguyen KD, Beachboard D.C., Kimbirauskas RK, et al. (2008) Distribution of Mycobacterium ulcerans in buruli ulcer endemic and non-endemic aquatic sites in Ghana. PLoS Negl Trop Dis 2: e205.