Victor Ocasio-Ramirez, PhD
272 Jones Bldg
Box 3580 DUMC
Durham, NC 27710
Phone: (919) 668-2450
Fax: (919) 681-9193
Recently genetic tools have been developed to genetically manipulate Chlamydia trachomatis, making this organism an attractive pathogen to work with. Currently I am working on understanding the secretion of Type III effectors and its effects during C. trachomatis infection. By using a combination of genetic, biochemical and biophysical methods I plan to characterize a number of effectors and in what order are delivered to the host cell.
In my free time I enjoy running. Also I love hiking and exploring new restaurants.
1) Salcedo, A., Del Valle, A., Sanchez, B., Ocasio, V., Ortiz, A., Marquez, P., Siritunga, D. (2010) Comparative evaluation of physiological post-harvest root deterioration of 25 Cassava (Manihot esculenta) accessions: visual vs. hydroxycoumarinns fluorescent accumulation analysis. Afr. J. Agric. Res., 5: 3138-3144.
2) Corrêa, F., Ko, W-H., Ocasio, V., Bogomolni, R.A. and Gardner, K.H. (2013) Blue light regulated two component systems: Enzymatic and functional analyses of Light-Oxygen-Voltage (LOV) histidine kinases and downstream response regulators. Biochemistry, 52: 4656-4666.
3) Echeverry-Solarte, M., OcasioV., Figueroa, A., Gonzalez, E. and Siritunga, D. (2013) Expression profiling of genes associated with Cyanogenesis in three Cassava cultivars containing varying levels of toxic cyanogens. Am. J. Plant Sci, 4: 1533-1545.
4) Ocasio, V., Corrêa, F. and Gardner, K.H. (2015) Ligand-Induced Folding of a Two-Component Signaling Receiver Domain. Biochemistry, 54: 1353-1363.