Lauren Davey, PhD
Box 3580 DUMC
272 Jones Building
Durham, NC 27710
Research Interest: I completed my PhD at Dalhousie University in Halifax, Canada, where I investigated the commensal oral bacterium Streptococcus gordonii. In 2016 I joined Raphael Valdivia’s lab where I am working with another commensal organism, Akkermansia muciniphila. A. muciniphila is a recently discovered inhabitant of the gut microbiota that is associated with metabolic health. The aim of my project is to develop genetic tools to better understand the basic mechanisms of A. muciniphila colonization and how it benefits its host.
Personal Interests: I spend my free time watching SpongeBob SquarePants and Dr. Who, playing Stars Wars video games, building Legos, checking out comic book stores, and hanging out with my 10 year old son.
L. Davey, S. A. Halperin, S. F. Lee. (2016) Thiol-disulfide exchange in Gram-positive Firmicutes. Trends in Microbiology. Article in press
L. Davey, S. A. Halperin, S. F. Lee. (2016) Mutation of the thiol-disulfide oxidoreductase SdbA activates the CiaRH two-component system leading to bacteriocin expression shutdown in Streptococcus gordonii. Journal of Bacteriology 198(2): 321-331
L. Davey, J. LeBlanc, A. Cohen, S. A. Halperin, S. F. Lee. (2016) The Streptococcus gordonii disulfide oxidase SdbA exhibits activity using a single C-terminal cysteine of the CXXC motif. Molecular Microbiology 99(2): 236–253
L. Davey, S. A. Halperin, S. F. Lee. (2015) Immunoblotting conditions for small peptides from streptococci. Journal of Microbiological Methods 114:40-42
L. Davey, C. K. W. Ng, S. A. Halperin, S. F. Lee. (2013) Functional analysis of paralogous thiol-disulfide oxidoreductases in Streptococcus gordonii. Journal of Biological Chemistry 288:16416-16429
S. R. Kurissery, N. Kanavillil, K.T. Leung, A. Chen, L. Davey, H. Schraft. (2010) Electrochemical and microbiological characterization of paper mill biofilms. Biofouling 26 (7): 799-808
M. Tian, N. Kanavillil, L. Davey, K. T. Leung, H. Schraft, A. Chen (2007) Direct growth of biofilms on an electrode surface and its application in electrochemical biosensoring. Journal of Electroanalytical Chemistry 611: 133–13