Marcio Jose Pocas Fonseca

Heitman – Lab Members

Sabbatical Professor
Department of Genetics and Morphology
University of Brasilia
Brazil
317 CARL Building
Phone: (919) 684-0278
Fax: (919) 684-2790
mpf22@duke.edu

Biography:

Dr. Marcio José Poças Fonseca (Marcio Poças) is B.Sc. in Biological Sciences (Cytogenetics applied to Pathology, 1990) from the University of Brasilia-Brazil; M. Sc. in Molecular Biology (1994) and PhD in Molecular Biology from the University of Brasilia in a joint program with the Vienna University of Technology (Austria, 2000). Associate Professor at the Department of Genetics and Morphology, Institute of Biological Sciences – University of Brasilia since 1997. Visiting researcher (Molecular and Micro-organisms Genetics) at the Institute of Chemical Engineering, Vienna University of Technology (August 2006 to October 2007) and at the Department of . Microbiology of the University of Delhi South Campus, India (January – March 2014; November 2014 – March 2015). His expertise in focused on gene structure, function and regulation in cellulolytic and pathogenesic fungi, with emphasis in epigenetic regulation. 24 full papers in international indexed journals, 08 book chapters, 02 patents on biotechnology, 13 M.Sc. as supervisor, 03 PhD as supervisor.

Publications:

Mello-de-Sousa, Thiago Machado; Rassinger, A; Derntl, C.; Poças-Fonseca, MJ, Mach, RL; Mach-Aigner, AR. The relation between promoter chromatin status, Xyr1, and cellulase expression in Trichoderma reesei. Current Genomics (accepted for publication).

Mello-de-Sousa TM; Rassinger A; Pucher ME, dos Santos Castro L; Persinoti GF, Silva-Rocha R; Poças-Fonseca MJ, Mach RL, Nascimento Silva R, Mach-Aigner AR. (2015). The impact of chromatin remodelling on cellulase expression in Trichoderma reesei. BMC Genomics. 16: 588. doi: 10.1186/s12864-015-1807-7.

Brandão FA, Derengowski LS, Albuquerque P, Nicola AM, Silva-Pereira I, Poças-Fonseca MJ. (2015). Histone deacetylases inhibitors effects on Cryptococcus neoformans major virulence phenotypes. Virulence 23: 1-13. 10.1080/21505594.2015.1038014.

Mello-de-Sousa, Thiago Machado; Gorshe, R.; Rassinger, A.; Poças-Fonseca, MJ.; Mach, R. L., Mach-Aigner, A.R. (2014). A truncated form of the Carbon catabolite repressor 1 increases cellulase production in Trichoderma reesei. Biotechnology for Biofuels. v.7, p.129 – .

TAVARES, E. Q. P.; RUBINI, Marciano Régis; MELLODESOUSA, Thiago Machado; DUARTE, G. C.; FARIA, F. P.; FERREIRA FILHO, Edivaldo Ximenes, KIAW, Cynthia Maria; SILVAPEREIRA, Ildinete; POÇAS-FONSECA, Marcio José. (2013). An Acidic Thermostable Recombinant Aspergillus nidulans Endoglucanase Is Active towards Distinct Agriculture Residues. Enzyme Research., v. p.1 – 10.

OLIVEIRA, Gisele S; Ulhoa, C.J.; SILVEIRA, Marcos Henrique Luciano; ANDREAUS, J.; SILVAPEREIRA, Ildinete; POÇAS-FONSECA, Marcio José, FARIA, Fabrícia Paula de. (2012). An alkaline thermostable recombinant Humicola grisea var. thermoidea cellobiohydrolase presents bifunctional (endo/exoglucanase) activity on cellulosic substrates. World Journal of Microbiology & Biotechnology Incorporating the MIRCEN Journal of Applied Microbiology and Biotechnology (Dordrecht. Online). v. 29, p.19 – 26.

PEREIRA, Luciana Oliveira; RUBINI, Marciano Régis; SILVA, J. R.; OLIVEIRA, D. M.; Izabel Cristina Rodrigues da Silva, POÇAS-FONSECA, M. J., AZEVEDO, Ricardo Bentes de. (2012) Comparison of stem cell properties of cells isolated from normal and inflamed dental pulps. International Endodontic Journal v. 45, p.01 – 12.

Mello-de-Sousa, Thiago Machado, Silva-Pereira, Ildinete, Poças-Fonseca, Marcio José (2011). Carbon source and pH-dependent transcriptional regulation of cellulase genes of Humicola grisea var. thermoidea grown on sugarcane bagasse. Enzyme and Microbial Technology. v. 48, p.19 – 26.

RUBINI, Marciano Régis; DILLON, Aldo José Pinheiro; KIAW, Cynthia Maria; FARIA, Fabrícia Paula de; POÇAS-FONSECA, M. J.; SILVAPEREIRA, Ildinete. (2010). Cloning, characterization and heterologous expression of the first Penicillium echinulatum cellulase gene. Journal of Applied Microbiology. v. 108, p.1187 – 1198.

Leliane M Souza, Juliana D Bittar, Izabel Cristina Rodrigues da Silva, Toledo, Orlando Airton, BRÍGIDO, Marcelo de Macedo, Poças-Fonseca, Marcio José. (2010). Comparative isolation protocols and characterization of stem cells from human primary and permanent teeth pulp. Brazilian Journal of Oral Sciences (Online). v.9, p.427 – 433.

Benoliel, Bruno, Poças-Fonseca, M. J., Torres, Fernando Araripe Gonçalves, Moraes, Lidia Maria Pepe. (2010). Expression of a Glucose-tolerant beta-glucosidase from Humicola grisea var. thermoidea in Saccharomyces cerevisiae. Applied Biochemistry and Biotechnology. v.160, p.2036 – 2044.

Mach-Aigner, Grosstessner-Hain, Poças-Fonseca, M. J, Mechtler, K., Mach, R. L. (2010). From an electrophoretic mobility shift assay to isolated transcription factors: a fast genomic-proteomic approach. BMC Genomics. v.11, p.644 -.

OLIVEIRAPEREIRA, L., BICALHO, Leandro Santos, LOPES, Mariana Campos da Paz, SOUSA, Thiago Machado Mello de, BÁO, Sônia Nair, SANTOS, Maria de Fátima Menezes de Almeida, POÇAS-FONSECA, M. J. (2008) DNA damage and Apoptosis induced by Pteridium aquilinum aqueous extract in the oral cell lines HSG and OSCC-3. Journal of Oral Pathology & Medicine. v.38, p.441 – 447.

LOPES, Mariana Campos da Paz, PEREIRA, Luciana Oliveira, BICALHO, Leandro Santos, José G Dórea, POÇAS-FONSECA, M. J., SANTOS, Maria de Fátima Menezes de Almeida. (2008). Interaction of Bracken-fern with Vitamin C in Human Submandibular and Oral Epithelium Cell Lines. Mutation Research. Genetic Toxicology and Environmental Mutagenesis. v.652, p.158 – 163.

Juliana Khoury, Inês S. Resck, POÇAS-FONSECA, M. J., OLIVEIRAPEREIRA, L., SOUSA, Thiago Machado Mello de, Adriano B B Oliveira, GRISÓLIA, César Koppe. (2007). Anticlastogenic Potential and Antioxidant Effects of an Aqueous Extract of Pulp from the Pequi Tree (Caryocar Brasiliensis Camb). Genetics and Molecular Biology. v.30, p.442 – 448.

LACAVA, Zulmira G M, LACAVA, Leandro M, POÇAS-FONSECA, M. J., SOUZA, Thiago M M, PEREIRA, Luciana O, SILVA, Osni, PELEGRINI, Fernando, SABOLOVIC, Domagoj, SESTIER, Claude, AZEVEDO, Ricardo B, BUSKE, Norbert, MORAIS, Paulo C. (2006). Magnetic Resonance and Light Microscopy Investigation of Raw Cells treated with Dextran-Based Magnetic Fluids. IEEE Transactions on Magnetics. v.42, p. 3599 – 3601.

REIS, Viviane Castelo Branco, TORRES, Fernando Araripe Gonçalves, POÇAS-FONSECA, M. J., DESOUZA, Marlene Teixeira, SOUZA, Diorge Paulo de, ALMEIDA, João Ricardo Moreira, MARINHOSILVA, Camila, PARACHIN, Nádia Skorupa, DANTAS, Alessandra da Silva, MELLODESOUZA, Thiago Machado, MORAES, Lídia Maria Pepe de. (2005). Cell cylce, DNA replication, repair and recombination in the dimorphic human pathogen fungus Paracoccidioides brasiliensis. Genetics and Molecular Research. v.4, p.232 – 250, 2005.

FELIPE, Maria Sueli Soares, TORRES, Fernando Araripe Gonçalves, MARANHÃO, Andréa Queiroz, SILVAPEREIRA, Ildinete, POÇAS-FONSECA, M. J., CAMPOS, Élida Geralda, MORAES, Lídia Maria Pepe de, ARRAES, Fabrício B M, CARVALHO, Maria José A, ANDRADE, Rosângela Vieira, JESUÍNO, Rosália S A, PEREIRA, Maristela, SOARES, Célia Maria de Almeida, BRÍGIDO, Marcelo de Macedo. (2005). Functional Genome of the Human Pathogenic Fungus Paracoccidioides brasiliensis. FEMS Immunology and Medical Microbiology. v.45, p.369 – 381.

ANDRADE, Rosângela Vieira, SILVA, Silvana Petrofeza da, TORRES, Fernando Araripe Gonçalves, POÇAS-FONSECA, M. J., PEREIRA, Ildinete Silva, MARANHÃO, Andréa Queiroz, CAMPOS, Élida Geralda, MORAES, Lídia Maria Pepe de, JESUÍNO, Rosália S A, PEREIRA, Maristela, SOARES, Célia Maria de Almeida, WALTER, Maria Emília M T, CARVALHO, Maria José A, ALMEIDA, Nalvo F, BRÍGIDO, Marcelo de Macedo, FELIPE, Maria Sueli Soares
(2005). Overview and Perspectives on the Transcriptome of Paracoccidioides brasiliensis. Revista Iberoamericana de Micología. v.22, p.194 – 2002.

FELIPE, Maria Sueli Soares, ANDRADE, Rosângela Vieira, ARRAES, Fabrício B M, NICOLA, André Moraes, MARANHÃO, Andréa Queiroz, TORRES, Fernando Araripe Gonçalves, PEREIRA, Ildinete Silva, POÇAS-FONSECA, M. J., CAMPOS, Élida Geralda, MORAES, Lídia Maria Pepe de, ANDRADE, Patrícia Albuquerque, TAVARES, Aldo Henrique, SILVA, Simoneide Souza, KYAW, Cynthia Maria, SOUZA, Diorge Paulo de, NETWORK, Pbgenome, PEREIRA, Maristela, JESUÍNO, Rosália S A, ANDRADE, Edmar Vaz, PARENTE, Juliana, OLIVEIRA, Gisele S, BARBOSA, Mônica S, MARTINS, Natália Florêncio, FACHIN, Ana L, CARDOSO, Renato S, PASSOS, Geraldo A S, ALMEIDA, Nalvo F, WALTER, Maria Emília M T, SOARES, Cecília M A, CARVALHO, Maria José A, BRÍGIDO, Marcelo de Macedo. (2005). Transcriptional Profiles of The Human Pathogenic Fungus Paracoccidiodes brasiliensis in Mycelium and Yeast Cells. The Journal of Biological Chemistry. v.280, p.24706 – 24714.

TAVARES, Aldo Henrique, SILVA, Simoneide Souza, BERNADES, Vanilce Vilmar, MARANHÃO, Andréa Queiroz, KYAW, Cynthia Maria, POÇAS-FONSECA, M. J., SILVAPEREIRA, Ildinete. (2005). Virulence insights on Paracoccidioides brasiliensis. Genetics and Molecular Research. v.4, p.372 – 389.

DEPAULA, E. H., POÇAS-FONSECA, M. J., AZEVEDO, Maristella de Oliveira. (2003). The product of Humicola grisea var. thermoidea cbh1.2 gene is the major expressed protein under induction by lignocellulosic residues. World Journal of Microbiology & Biotechnology. v.19, p.631 – 635.

FELIPE, Maria Sueli Soares, ANDRADE, Rosângela Vieira, SILVA, Silvana Petrofeza da, MARANHÃO, A Q , TORRES, Fernando Araripe Gonçalves, ALBUQUERQUE, Patrícia, ARRAES, Fabrício B M, ARRUDA, M , AZEVEDO, Maristella de Oliveira, BAPTISTA, Alessandra Jorge, BATAUS, L A M , BORGES, C L , CAMPOS, E G , DAHER, B S , DANTAS, A , FERREIRA, M A, POÇAS-FONSECA, M. J. et al (2003). Transcriptome Characterizationof the Dimorphic and Pahtogenic Fungus Paracoccidioides brasiliensis by EST Analysis. Yeast (Chichester, England. Print). v.20, p.263 – 271.

POÇAS-FONSECA, M. J., PEREIRA, Ildinete Silva, ROCHA, Bruno Benoliel, AZEVEDO, Maristella de Oliveira. (2000) Substrate-dependent differential expression of Humicola grisea var. thermoidea cellobiohydrolase genes. Canadian Journal of Microbiology (Print). v.46, p.749 – 752.

POÇAS-FONSECA, M. J., LIMA, B. D., BRÍGIDO, Marcelo de Macedo, PEREIRA, Ildinete Silva, FELIPE, Maria Sueli Soares, RADFORD, A., AZEVEDO, Maristella de Oliveira. (1997). Humicola grisea var. thermoidea cbh1.2: A New Gene in the Family of Cellobiohydrolases is Expressed and Encodes a Cellulose-Binding Domain-Less Enzyme. Journal of General and Applied Microbiology. v.43, p.115 – 120.