Eve Chow

Heitman – Lab Members

Eve Chow Post-Doctoral Fellow Post-Doctoral Fellow
317 CARL Building
Box 3546 DUMC
Durham, N.C. 27710
Phone: 919.684.2809
Fax: 919.684.2790

I recently obtained my PhD in Biochemistry from the University of Queensland, Australia, where I worked under the supervision of Dr. James Fraser. My doctoral thesis was focused on the subtelomeric microevolution of Cryptococcus neoformans var. grubii that could be taking place during the course of infection. Since C. neoformans have been shown to undergo genomic changes during infection, I was interested in determining if some of these changes may be taking place in the subtelomeres that could contribute to the persistence of infection. During my doctoral training, I became interested in the different mechanisms of heterochromatin formation employed by different organisms, including RNAi-RITS pathway that is employed by Schizosaccharomyces pombe. After the completing my doctoral training, I decided to continue investigating the different characteristics of C. neoformans, moving away from the subtelomeric regions. One of the things I would like to investigate in the Heitman lab is the role that the RNAi-based pathways may play in C. neoformans during mitotic and sexual development and in gene silencing.