Hiroaki Matsunami, PhD – Publications

Professor

Google Scholar Profile 

research • biography • lab members • publications

Representative Publications:

Dey, S., Chamero, P., Pru, J.K., Chien, M.S., Ibarra-Soria, X., Spencer, K.R., Logan, D.W., Matsunami, H., Peluso, J.J., and Stowers, L. (2015). Cyclic Regulation of Sensory Perception by a Female Hormone Alters Behavior. Cell 161, 1334-1344.

Jiang, Y., Li, Y.R., Tian, H., Ma, M., and Matsunami, H. (2015). Muscarinic acetylcholine receptor M3 modulates odorant receptor activity via inhibition of beta-arrestin-2 recruitment. Nat Commun 6, 6448.

Ho, J., Perez-Aguilar, J.M., Gao, L., Saven, J.G., Matsunami, H., and Eckenhoff, R.G. (2015). Molecular recognition of ketamine by a subset of olfactory G protein-coupled receptors. Sci Signal 8, ra33.

Mainland, J.D., Keller, A., Li, Y.R, Zhou, T. Snyder, L.L., Moberly, A.H., Adipietro, K.A., Liu, W.L.L., Zhuang, H., Zhan, S., Lee, S.S., Lin, A., and H. Matusunami. (2014). The missense of smell: Functional variability in the human odorant receptor repertoire. Nat Neurosci, Jan;17(1):114-120. [Epub 2013 Dec 8].

Adipietro, K.A., J.D. Mainland, and H. Matsunami. (2012). Functional evolution of mammalian odorant receptors. PLoS Genet, 8(7):e1002821.

Dey, S. and H. Matsunami. (2011). Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors. Proc Natl Acad Sci U S A, 108(40):16651-16656.

Li, Y.R. and H. Matsunami (2011). Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling. Sci Signal, 4(155): ra1.

Zhuang, H., Chien, M.S., Matsunami, H. (2009). Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates. Proc Natl Acad Sci U S A, 106:21247-21251.

Saito, H., Chi, Q., Zhuang, H., Matsunami, H., Mainland, J.D. Odor coding by a mammalian receptor repertoire. (2009). Sci Signal, 2:ra9.

Zhuang, H., and Matsunami, H. (2008). Evaluating cell-surface expression and measuring activation of mammalian ordorant receptors in heterologous cells. Nat Protoc, 3: 1402-1413.

Keller, A., Zhuang, H., Chi, Q., Vosshall, L.B., Matsunami, H. (2007). Genetic variation in a human odorant receptor alters odour perception. Nature, 449: 468-472.

Hu, J., Zhong, C., Ding, C., Chi, Q., Walz, A., Mombaerts, P., Matsunami, H., Luo, M. (2007). Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem in the mouse. Science, 317:953-957.

Zhuang, H., and Matsunami, H. (2007). Synergism of accessory factors in functional expression of mammalian odorant receptors. J Biol Chem, 282:15284-15293.

Ishimaru, Y., Inada, H., Kubota, M., Zhuang, H., Tominaga, M., Matsunami, H. (2006). Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. Proc Natl Acad Sci U S A, 103:12569-12574.

Saito, H., Kubota, M., Roberts, R.W., Chi, Q., and Matsunami, H. (2004). RTP family members induce functional expression of mammalian odorant receptors. Cell, 119:679-691.

Matsunami H., Montmayeur, J.P. and Buck, L.B. (2000). A family of candidate taste receptors in human and mouse. Nature, 404:601-604.

Matsunami, H. and Buck, L.B. (1997). A multigene family encoding a diverse array of putative pheromone receptors in mammals. Cell, 90:775-784.

For a complete listing of publications, click here.