Debra Silver, PhD – Publications

Associate Professor
Duke Institute for Brain Sciences Investigator

research • biography • lab members • publications • lab website

Representative Publications:

  1. Pilaz, LJ*, McMahon, JJ*, Miller, EE, Lennox, AL, Suzuki, A, Salmon, E, Silver, DL, Prolonged mitosis of neural progenitors alters cell fate in the developing brain. Jan 6; 89(1):83-99. 2016. *co-first authors.

Pilaz, L-J, Lennox, A.L., Rouanet, J.P., and Silver, DL. Dynamic mRNA transport and local translation in radial glial progenitors of the developing brain. Current Biology. Online Nov. 30. pii: S0960-9822(16)31266-0. PMID: 27916527. 26: 1-10.

Mao, H*, McMahon, JJ*, Tsai, Y-H., Wang, Z, and Silver, DL. Haploinsufficiency for core exon junction complex components disrupts neurogenesis and causes p53-mediated microcephaly. PLOS Genetics. Sept. 12.; 12(9): e1006282. 2016 * co-first authors.

Mao, H, Brown, H, and Silver, DL. Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex. RNA. Online Oct. 25. pii: rna.058826.116. PMID: 27780844.

Pilaz, LJ and Silver, DL . Post-transcriptional regulation in corticogenesis: How RNA binding proteins help build the brain. WIREs RNA. June 18, 2015. Review.

Silver J of Neuro Cover_May 6 2015Mao, H, Pilaz, LJ, McMahon, J, Golzio, C, Wu, D, Shi, L, Katsanis, N, and Silver, DL Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly. Journal of Neuroscience. May 6; 35(18): 7003-7018. 2015. (Featured on cover and in News and Views in same issue).



Boyd, JL, Skove, SL, Rouanet, JP, Pilaz, L-J, Bepler, T, Gordân, R, Wray, GA, and Silver, DL. Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex. Current Biology. Mar 16; 25 (6) 772-9. 2015

Photo of NPR link for publication page-Debby Silver



McMahon JJ, Shi L, and Silver DL. Generation of a Magoh conditional allele in mice. Genesis. Aug; 52(8): 752-8. 2014

Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, Lerman-Sagie T, Leshinsky-Silver E, Anikster Y, Ben-Asher E, Olender T, Colleaux L, Décarie JC, Blaser S, Banwell B, Joshi RB, He XP, Patry L, Silver RJ, Dobrzeniecka S, Islam MS, Hasnat A, Samuels ME, Aryal DK, Rodriguiz RM, Jiang YH, Wetsel WC, McNamara JO, Rouleau GA, Silver DL, Lancet D, Pras E, Mitchell GA, Michaud JL, Goldstein DB. Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. Neuron Oct 16; 80(2): 429-41. 2013

Silver, DL, Watkins-Chow, D Schreck, K, Pierfelice, T, Larson, DM, Burnetti, A, Liaw, H, Myung, K, Walsh, CA, Gaiano, N, and Pavan, WJ. The exon junction complex component, Magoh, controls brain size by regulating neural stem cell division. Nature Neuroscience. May; 13(5):551-558. 2010
(Accompanying News and Views by Dave, KA. Regulating Brain Size Nature Neuroscience, May; 13(5):531. 2010)

To view a complete list of publications, click here.