Brooke D’Arcy

Silver Lab Members

Brooke D'Arcy Graduate Student (2017)
DUMC Box 3175
223 CARL Building
Durham, NC 27710
Phone: 919-613-2011
Fax: 919-684-2790


Research Interest: I grew up near Buffalo, NY and earned my B.S in Biochemistry from the Rochester Institute of Technology (RIT) in 2017. While at RIT, I worked in the lab of Dr. Lea Vacca Michel studying the orientation and function of bacterial lipoproteins. My project focused on peptidoglycan associated lipoprotein (pal) which is expressed in E.coli. We discovered that pal exhibits a unique dual orientation so that a population is expressed on the bacterial surface while a second population faces inward and interacts with the peptidoglycan layer. Additionally, we implicated an important role for pal in the pathogenesis of gram negative sepsis. I came to Duke through the Cell and Molecular Biology program. In March 2018 I joined Debby Silver’s lab where I will be studying mRNA localization and local translation in Radial Glia as well as the impact of Zika Virus on the functionality of the Exon Junction Complex.

Personal Interests: In my spare time I enjoy cooking, reading, hiking, and hanging out with my cats, Hank and Merle.