Clare Smith, PhD – Publications

Assistant Professor

researchbiography • lab members • alumni • publications • lab websitetwitter 

 

Smith CM*, Proulx MK*, Lai R*, Kiritsy MC, Bell TA, Hock P, Pardo-Manuel de Villena F, Ferris MT, Baker RE, Behar SM and Sassetti CM. “Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice” 2019. bioRxiv: https://doi.org/10.1101/785725; https://doi.org/10.1128/mBio.02791-19
*Denotes equal contributions

Siddharth S, Zaveri A, Dejesus MA, Smith CM, Baker RE, Ehrt S, Schnappinger D, Sassetti CM and Ioerger TR. “Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression” 2019. bioRxiv: https://doi.org/10.1101/590281; https://doi.org/10.1186/s12859-019-3156-z

Bellerose MM, Baek SH, Huang CC, Moss CE, Koh EI, Proulx MK, Smith CM, Baker RE, Lee JS, Eum S, Shin SJ, Cho SN, Murray M, Sassetti CM. “Common Variants in the glycerol kinase gene reduce tuberculosis drug efficacy”. 2019 https://doi.org/10.1128/mBio.00663-19

Smith CM and Sassetti CM. “Modeling diversity: do homogenous lab strains limit discovery?” 2018. https://doi.org/10.1016/j.tim.2018.08.002

Olive AJ, Smith CM, Kiritsy M and Sassetti CM. “The Phagocyte Oxidase controls tolerance to Mycobacterium tuberculosis infection”. 2018. bioRxiv https://doi.org/10.1101/232777; https://doi.org/10.4049/jimmunol.1800202

Mishra BB, Lovewell R, Olive AJ, Zhang G, Wang W, Smith CM, Phuah JY, Long JE, Dubuke M, Palace S, Goguen JD, Baker JE, Nambi S, Mishra R, Booty MG, Baer C, McCormick B, Chen X, and Sassetti CM. Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis. 2017. https://doi.org/10.1038/nmicrobiol.2017.72

DeJesus M, Nambi S, Smith CM, Baker RE, Sassetti CM and Loerger TR. Statistical analysis of genetic interactions in TnSeq data. 2017. https://doi.org/10.1093/nar/gkx128

Smith CM, Proulx MK, Olive AJ, Laddy D, Mishra BB, Moss C, Gutierrez NM, Bellerose MM, Barreira-Silva P, Phuah JY, Baker RE, Behar SM, Kornfeld H, Evans TG, Beamer G and Sassetti CM. Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype. 2016. bioRxiv https://doi.org/10.1101/064253; https://doi.org/10.1128/mBio.01516-16

Smith CM, Jerkovic T, Trong T, McCarthy J, Foote SJ and McMorran BJ. Griseofulvin impairs intraerythrocytic growth of Plasmodium falciparum through ferrochelatase inhibition but lacks activity in an experimental human infectivity study. 2016. https://doi.org/10.1038/srep41975

Gonzales NM, Howell VM and Smith CM*. 29th International Mammalian Genome Conference meeting report. 2016. https://doi.org/10.1007/s00335-016-9640-0
*Corresponding author

Smith CM, Jerkovic A, Puy H, Winship I, Deybach JC, Gouya L, van Dooren G, Goodman CD, Sturm A, Manceau H, McFadden GI, David P, Mercereau-Puijalon O, Burgio G, McMorran BJ, Foote SJ. Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites. 2015. https://doi.org/10.1182/blood-2014-04-567149

Brizuela M, Huang HM, Smith C, Burgio G, Foote SJ, McMorran BJ. Treatment of Erythrocytes with the 2-Cys Peroxiredoxin Inhibitor, Conoidin A, Prevents the Growth of Plasmodium falciparum and Enhances Parasite Sensitivity to Chloroquine. 2014. https://doi.org/10.1371/journal.pone.0092411

McMorran BJ, Wieczorski L, Drysdale K, Chan J, Huang H, Smith CM, Mitiku C,  Beeson JB, Burgio G, Foote SJ. Platelet Factor 4 and Duffy Antigen Required for Platelet Killing of Plasmodium falciparum. 2012. https://science.sciencemag.org/content/338/6112/1348

Longley R, Smith C, Fortin A, Berghout J, McMorran B, Burgio G, Foote S and Gros P. Host resistance to malaria using mouse models to explore the host response. 2011. https://doi.org/10.1007/s00335-010-9302-6
(Invited review).