Carolyn Coyne, PhD – Biography
Dr. Carolyn Coyne was trained in pharmacology and has graduate and post-graduate training in cell biology and microbiology. Dr. Coyne received a B.S. in Biochemistry from Florida State University and then completed her doctoral work in 2003 at the University of North Carolina at Chapel Hill. Her doctoral thesis investigated the impact of inflammation on intercellular junctions in human airway epithelial cells. Dr. Coyne completed a postdoctoral fellowship in the Department of Microbiology/Division of Pediatric Infectious Diseases at the University of Pennsylvania/Children’s Hospital of Philadelphia. Dr. Coyne joined the faculty of the University of Pittsburgh in 2007 as an Assistant Professor, was promoted to Associate Professor with tenure in 2012, and became a Full Professor in the Department of Pediatrics in 2019. Dr. Coyne is the Director for the Center for Microbial Pathogenesis within the Children’s Hospital of Pittsburgh at UPMC and an Associate Director of the Richard King Mellon Pediatric Research Institute. Dr. Coyne’s research program focuses on the mechanisms by which cellular barriers restrict microbial infections and the strategies that microbes have evolved to penetrate these barriers. She is a recognized leader in the field of virus infections of polarized cells, host innate immune signaling, and host-pathogen interactions at the maternal-fetal interface. Dr. Coyne’s work is multidisciplinary and encompasses cell biology, tissue engineering, immunology, and microbiology to dissect the complex dialogue that occurs between virus and host during the course of infection.