Ananda Vasudevan

Cullen Lab

Post-Doctoral Fellow
423 CARL Bldg.
BOX 3025
Durham, NC 27710
Phone:919-684-5656
ananda.ayyappan@duke.edu

 

Research Interest:
Anand is currently working on Viral Epitranscriptomics at Cullen lab, MGM. He is mainly focused on Molecular Retrovirology and studied APOBEC3 (A3) DNA deaminases versus Retroviruses in his PhD work at Münk lab, HHU, Düsseldorf. Besides, he investigated A3B and class IIA HDAC enzymes in urothelial carcinoma at Schulz lab, HHU and a bit of MX proteins before joining Duke.

Publication List:

Jaguva Vasudevan, A. A., Hoffmann, M. J., Beck, M. L. C., Poschmann, G., Petzsch, P., Wiek, C., Stühler, K., Köhrer, K., Schulz, W. A., and Niegisch, G. (2019) HDAC5 expression in urothelial carcinoma cell lines inhibits long-term proliferation but can promote epithelial-to-mesenchymal transition. Int. J. Mol. Sci. 20, 2135

Osei Kuffour, E., Schott, K., Jaguva Vasudevan, A. A., Holler, J., Schulz, W. A., Lang, P. A., Lang, K. S., Kim, B., Häussinger, D., Konig, R., and Münk, C. (2018) USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1. J Virol

Meier, K., Jaguva Vasudevan, A. A., Zhang, Z., Bahr, A., Kochs, G., Häussinger, D., and Münk, C. (2018) Equine MX2 is a restriction factor of equine infectious anemia virus (EIAV). Virology 523, 52-63

Jaguva Vasudevan, A. A*., Bähr, A*., Grothmann, R., Singer, A., Häussinger, D., Zimmermann, A., and Münk, C. (2018) MXB inhibits murine cytomegalovirus. Virology 522, 158-167 (*equal contribution)

Kaletsch, A., Pinkerneil, M., Hoffmann, M. J., Jaguva Vasudevan, A. A., Wang, C., Hansen, F. K., Wiek, C., Hanenberg, H., Gertzen, C., Gohlke, H., Kassack, M. U., Kurz, T., Schulz, W. A., and Niegisch, G. (2018) Effects of novel HDAC inhibitors on urothelial carcinoma cells. Clin Epigenetics 10, 100

Jaguva Vasudevan, A. A#., Kreimer, U., Schulz, W.A., Krikoni, A., Schumann, G.G., Häussinger, D., Münk, C., and Goering, W#. (2018) APOBEC3B activity is prevalent in urothelial carcinoma cells and only slightly affected by LINE-1 expression. Front. Microbiol. 9, 2088 (# corresponding authors)

Jaguva Vasudevan, A. A., Goering, W., Häussinger, D., and Münk, C. (2018) Detection of APOBEC3 Proteins and Catalytic Activity in Urothelial Carcinoma. Methods Mol Biol 1655, 97-107 (Non-peer reviewed)

Jaguva Vasudevan, A. A., Hofmann, H., Willbold, D., Häussinger, D., Koenig, B. W., and Münk, C. (2017) Enhancing the Catalytic Deamination Activity of APOBEC3C Is Insufficient to Inhibit Vif-Deficient HIV-1. J Mol Biol 429, 1171-1191

Marino, D*., Perkovic, M*., Hain, A*., Jaguva Vasudevan, A. A*., Hofmann, H., Hanschmann, K. M., Muhlebach, M. D., Schumann, G. G., Konig, R., Cichutek, K., Häussinger, D., and Münk, C. (2016) APOBEC4 Enhances the Replication of HIV-1. PLoS One 11, e0155422 (*equal contribution)

Zhang, Z., Gu, Q., Jaguva Vasudevan, A. A., Hain, A., Kloke, B. P., Hasheminasab, S., Mulnaes, D., Sato, K., Cichutek, K., Häussinger, D., Bravo, I. G., Smits, S. H., Gohlke, H., and Münk, C. (2016) Determinants of FIV and HIV Vif sensitivity of feline APOBEC3 restriction factors. Retrovirology 13, 46

Zhang, Z., Gu, Q., Jaguva Vasudevan, A. A., Jeyaraj, M., Schmidt, S., Zielonka, J., Perkovic, M., Heckel, J. O., Cichutek, K., Häussinger, D., Smits, S. H., and Münk, C. (2016) Vif Proteins from Diverse Human Immunodeficiency Virus/Simian Immunodeficiency Virus Lineages Have Distinct Binding Sites in A3C. J Virol 90, 10193-10208

Bähr, A., Singer, A., Hain, A., Jaguva Vasudevan, A. A., Schilling, M., Reh, J., Riess, M., Panitz, S., Serrano, V., Schweizer, M., Konig, R., Chanda, S., Haussinger, D., Kochs, G., Lindemann, D., and Münk, C. (2016) Interferon but not MxB inhibits foamy retroviruses. Virology 488, 51-60

Maney, S. K., McIlwain, D. R., Polz, R., Pandyra, A. A., Sundaram, B., Wolff, D., Ohishi, K., Maretzky, T., Brooke, M. A., Evers, A., Jaguva Vasudevan, A. A., Aghaeepour, N., Scheller, J., Münk, C., Häussinger, D., Mak, T. W., Nolan, G. P., Kelsell, D. P., Blobel, C. P., Lang, K. S., and Lang, P. A. (2015) Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17. Sci Signal 8, ra109

Widera, M., Hillebrand, F., Erkelenz, S., Jaguva Vasudevan, A. A., Münk, C., and Schaal, H. (2014) A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction. Retrovirology 11, 72

Horn, A. V., Klawitter, S., Held, U., Berger, A., Jaguva Vasudevan, A. A., Bock, A., Hofmann, H., Hanschmann, K. M., Trosemeier, J. H., Flory, E., Jabulowsky, R. A., Han, J. S., Lower, J., Lower, R., Münk, C., and Schumann, G. G. (2014) Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity.Nucleic Acids Res 42, 396-416

Jaguva Vasudevan, A. A*., Perkovic, M*., Bulliard, Y., Cichutek, K., Trono, D., Häussinger, D., and Münk, C. (2013) Prototype foamy virus Bet impairs the dimerization and cytosolic solubility of human APOBEC3G. J Virol 87, 9030-9040 (*equal contribution)

Jaguva Vasudevan, A. A., Smits, S. H., Hoppner, A., Häussinger, D., Koenig, B. W., and Münk, C. (2013) Structural features of antiviral DNA cytidine deaminases. Biol Chem 394, 1357-1370

Kopietz, F., Jaguva Vasudevan, A. A., Kramer, M., Muckenfuss, H., Sanzenbacher, R., Cichutek, K., Flory, E., and Münk, C. (2012) Interaction of human immunodeficiency virus type 1 Vif with APOBEC3G is not dependent on serine/threonine phosphorylation status. J Gen Virol 93, 2425-2430