427 CARL Building
Durham, N.C. 27710
I received my PhD from the University of Oklahoma Health Sciences Center. My dissertation focus was on the role of bacterial cell wall components from Bacillus anthracis in late-stage anthrax pathogenesis. I joined the Heaton lab because I have always wanted to pursue research in the field of virology and viral pathogenesis. Currently, I am focused on the development of better influenza vaccines that provide broad cellular and humoral protection from infection. I am also interested in influenza pathogenesis and how our immune system contributes to disease severity and outcome. I hope to apply the knowledge I gain here to develop therapeutics for other emerging viral pathogens.
Outside of lab I enjoy sports (football, soccer, and baseball), movies, music, reading and spending time with my wife and our 3 pups. I consider myself and amateur paleontologist. I also enjoy learning as much as I can about birds of prey and would like to take up falconry someday. I am also into venomous reptiles. I also enjoy cooking and grilling out.
Popescu, N. I., Silasi, R., Keshari, R., Girton, A., Burgett, T., Zeerleder, Gailani, D., S., Gruber, A., Lupu, F., and Coggeshall, K. M. Peptidoglycan induces disseminated intravascular coagulation in non-human primates through activation of both coagulation pathways. Blood, 132(8): 849-60, June 2018.
Girton, A. W., Popescu, N. I., Keshari, R. S., Burgett, T., Lupu, F., Coggeshall, K. M. Serum amyloid P and IgG exhibit differential capabilities in the activation of the innate immune system in response to Bacillus anthracis peptidoglycan. Infection and Immunity, 86(5): e00076-18, March 2018.
Langer, M., Girton, A. W., Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2. PlosOne, 13(2): e0193207: February 2018 – co-first author
Budda, S., Girton, A., Henderson, J.G., and Zenewicz, L.A. Transcription Factor HIF-1α controls expression of the cytokine IL-22 in CD4 T Cells. The Journal of Immunology, 197(7): 2646-52, August 2016.
Pierce, R.D., Kim, E.S., Girton, L., Mcmurry, J.L., Francis, J.W., and Albrecht, E.A. Characterization of crude Echis carinatus venom-induced cytotoxicity in HEK 293T cells. Journal of Venom Research, 2: 59-67, December 2011.