Fred Dietrich, PhD
Associate Professor
Department of Molecular Genetics and Microbiology
biography  •  lab members  •  website

Selected Publications:

• Christman MF, Dietrich FS, Fink GR. (1988). Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Cell 55:413-42.
  
  
• Saleh FMA, Bishop DJ, Dietrich FS, Knezovich JP, Harrison FL. (1990). Transport of nonabsorbed chemicals in the subsurface environment: proposed model with experimental verification. Soil Science 149:23-34.
  
  
• Christman MF, Dietrich FS, Levin NA, Sadoff BU, Fink GR. (1993). The rRNA-encoding DNA array has an altered structure in topoisomerase I mutants of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 90:7637-7641.
  
  
• Oefner PJ, Hunicke-Smith SP, Chiang L, Dietrich FS, Mulligan J, Davis RW. (1996). Efficient random subcloning of DNA sheared in a recirculating point-sink flow system. Nucleic Acids Res 24:3879-3886.
  
  
• Jacq C, Alt-Morbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Blocker H, Blugeon C, Boskovic J, Brandt P, Bruckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P, et al. (1997). The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Nature 387(6632 Suppl.):75-78.
  
  
• Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Bruckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J, et al. (1997). The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. Nature 387(6632 Suppl):103-105.
  
  
• Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkaris D, Lew H, Lin D, Mosedale D, Davis RW, et al. (1997). The nucleotide sequence of Saccharomyces cerevisiae chromosome V. Nature 387(6632 Suppl):78-81.
  
  
• Wendland J, Pohlamm R, Dietrich FS, Steiner S, Mohr C, Philippsen P. (1999). Compact organization of rRNA genes in the filamentous fungus Ashbya gossypii. Current Genetics 35:618-625.
  
  
• Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM Connelly C, Davis K, Dietrich FS, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G, Hegemann JH, Jones T, Laub M, Liao H, Davis RW, et al. (1999). Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 5429:901-906.
  
  
• Ayad-Durieux Y, Knechtle P, Dietrich FS, Philippsen P. (2000). A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii. J. Cell. Science 113:4563-4575.
  
  
• Alberti-Sequi C, Dietrich FS, Altmann-Johl R, Heopfner D, Philippsen P. (2001). Cytoplasmic dynein is required to oppose the force that moves nuclei towards the hyphal tip in the filamentous ascomycete Ashbya gossypii. J. Cell. Science 114:975-986.
  

• Lengeler KB, Fox DS, Fraser JA, Allen A, Forrester K, Dietrich FS, Heitman J. (2002). Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. Eukaryotic Cell 1: 704-718.
  
  
• Jarvis ED, Smith VA, Wada K, Rivas MV, McElroy M, Smulders TV, Carninci P, Hayashizaki Y, Dietrich FS, Wu X, McConnell P, Yu J, Wang PP, Hartemink AF, Lin S. (2002). A framework for integrating the songbird brain. J. Comp Physiology 188:961-980.
  
  
• Hauser MA, Li YJ, Takeuchi S, Walters R, Noureddine M, Maready M, Danden T, Hulette C, Martin E, Hauser E, Xu H, Schmechel D, Stenger JE, Dietrich FS, Vance J. (2003). Genomic convergence: identifying candidate genes for Parkinson’s disease by combining serial analysis of gene expression and genetic linkage. Human Molecular Genetics 12:671-677.
  
  
• Toffaletti DL, Dei Poeta M, Rude TH, Dietrich FS, Perfect JR. (2003). Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus by temperature and host environment. Microbiology. 149:1041-1049.
  
  
• Zhang Z, Dietrich FS. (2003). Verification of a new gene on Saccharomyces cerevisiae chromosome III. Yeast 20:731-738.
  
  
• Brachat S, Dietrich FS, Voegeli S, Zhang Z, Stuart L, Lerch A, Gates K, Gaffney T, and Philippsen P. (2003). Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4:R45 [Epub].
  
  
• Knechtle P, Dietrich, FS, Philippsen, P. (2003). Maximal polar growth potential depends on the polarisom component AGSpa2 in the filamentous fungus Ashbya gossypii. Mol Biol Cell [Epub ahead of print].
  
  
• Dietrich FS, Voegeli S, Brachat S, Lerch A, Gates K, Steiner S, Mohr C, Pohlmann R, Luedi P, Choi S, Wing RA, Flavier A, Gaffney TD, and Philippsen P. (2004). The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome. Science 304:304-307. [Epub 2004 Mar 04].
  
  
• Toffaletti DL, Nielsen K, Dietrich FS, Heitman, J and Perfect, JR. (2004). Cryptococcus neoformans mitochondrial genomes from serotype A and D strains do not influence virulence. Current Genetics 46:193-204.
  
  
• Kraus PR, Boily MJ, Giles SS, Stajich JE, Allen A, Cox GM, Dietrich FS, Perfect JR, and Heitman J. (2004). Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarray. Eukaryotic Cell 3:1249-1260.
  
  
• Fraser JA, Diezmann S, Subaran RL, Allen A, Lengeler KB, Dietrich FS, and Heitman J. (2004). Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. PLoS Biology 2:e384. [Epub Nov 9, 2004].
  
  
• Campbell LT, Fraser JA, Nichols CB, Dietrich FS, Carter D, and Heitman J. (2005). Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. Eukaryotic Cell 4:1410-1419.
  
  
• Fraser JA, Giles SS, Wenink EC, Geunes-Boyer SG, Wright JR, Diezmann S, Allen A, Stajich JE, Dietrich FS, Perfect JR, Heitman J. (2005). Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak. Nature Oct 27;437(7063):1360-4. [Epub 2005 Oct 9].
  
  
• Zhang Z and Dietrich FS. (2005). Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE. Nucleic Acids Res. 19:2838-2851.

• Hall C, Brachat S, and Dietrich FS. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryotic Cell 4:1102-1115.
  
  
• Zhang Z and Dietrich FS. (2005). Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae. Current Genetics 13:1-11. [Epub ahead of print].
  
  
• Giles SS, Stajich JE, Nichols C, Gerrald QD, Alspaugh JA, Dietrich F, Perfect JR. (2006). The Cryptococcus neoformans catalase gene family and its role in antioxidant defense. Eukaryot Cell. Sep;5(9):1447-59.
  
  
• Cramer RA Jr, Stajich JS, Yamanaka Y, Dietrich FE, Steinbach WJ, Perfect JR. (2006). Phylogenomic analysis of non-ribosomal peptide synthetases in the genus Aspergillus. Gene Jul 21; [Epub ahead of print].
  
  
• Kavanaugh LA, Fraser JA, Dietrich FS. (2006). Evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment. Mol Biol Evol. Oct;23(10):1879-90. [Epub 2006 Jul 26].
  
  
• Fraser JA, Lim SM, Diezmann S, Wenink EC, Arndt CG, Cox GM, Dietrich FS, Heitman J. (2006). Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale. FEMS Yeast Res. Jun;6(4):620-4.
  
  
• Stajich JE, Dietrich FS. (2006). Evidence of mRNA-mediated intron loss in the human-pathogenic fungus Cryptococcus neoformans. Eukaryot Cell May;5(5):789-93.