Part of the Duke
Institute for Genome Sciences and Policy
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ABOUT THE CENTER The Duke DNA Microarray Center, a component of the Duke Center for Genome Technology, was established to provide the infrastructure to enable the development of major projects that utilize DNA microarrays for the large scale analysis of gene expression. Moreover, the Center is also the home for the Duke Genome Core Facility that provides microarray analysis services to investigators at Duke. The DNA Microarray Center currently employs two technologies for gene expression analysis — Affymetrix GeneChip arrays and custom-produced spotted DNA microarrays. To date, all of the major projects developed through the DNA Microarray Center have made use of Affymetrix arrays, both human and mouse. Nevertheless, the development of specialized arrays to examine gene expression in tissues of interest for NIDDK-supported investigators, as well as neurological-focused studies, are making use of custom printed arrays. In addition to the generation and assay of DNA microarrays, the DNA Microarray Center also provides a base for the development of computational tools for the analysis of gene expression data as well as database systems for storage and further analysis of the results of expression experiments.
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