Faculty and Research

Micah Luftig, PhD
Assistant Professor
Deputy Director, Center for Virology
research  biography • lab members • alumni • publications  lab website

 

Representative Publications:

  • Nikitin, P.A., Price, A.M., McFadden, K., Yan, C.M., Luftig MA. (2014). “Mitogen-induced B-cell proliferation activates Chk2-dependent G1/S cell cycle arrest.” PLoS One. 2014 Jan 30;9(1):e87299. [Abstract] [Article]

  • Price, A.M., Luftig, M.A. (2014). “Dynamic Epstein-Barr virus gene expression on the path to B-cell transformation.” Adv Virus Res. 88:279-313. [Abstract]

  • Olive, V., Sabio, E., Bennett, M.J., De Jong, C.S., Biton, A., McGann, J.C., Greaney, S.K., Sodir, N.M., Zhou, A.Y., Balakrishnan, A., Foth, M., Luftig, M.A., Goga, A., Speed, T.P., Xuan, Z., Evan, G.I., Wan, Y., Minella, A.C., He, L. (2013). “A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.” Elife. Oct 15;2:e00822. [Abstract]

  • Homa, N.J., Salinas, R., Forte, E., Robinson, T.J., Garcia-Blanco, M.A., Luftig, M.A. (2013). "Epstein-Barr virus induces global changes in cellular mRNA isoform usage important for the maintenance of latency." J Virol. 2013 Sep 11. [Epub ahead of print] [Abstract]

  • McFadden, K., Luftig, M.A. "Interplay between DNA tumor viruses and the host DNA damage response." (2013). Curr Top Microbiol Immunol. 371:229-57. Review. [Abstract]

  • Price, A.M., J.P. Tourigny, E. Forte, R. E. Salinas, S.S. Dave, Luftig, M.A. (2012). "Analysis of EBV-Regulated Host Gene Expression Changes through Primary B-Cell Outgrowth Reveals Delayed Kinetics of LMP1-Mediated NFΚB Activation." J Virol. 86(20):11096-106.[Abstract] [PDF]

  • Robinson, T.J., E. Forte, R.E. Salinas, S. Puri, M. Marengo, M.A. Garcia-Blanco, Luftig, M.A. (2012). "SplicerEX: A tool for the automated detection and classification of mRNA changes from conventional and splice-sensitive microarray expression data." RNA. 18(8):1435-45.[Abstract] [PDF]

  • Nikitin, P.A., Luftig, M.A. (2012). “The DNA damage response in viral-induced cellular transformation. Br J Cancer. 106:429-435. [Abstract] [PDF]

  • Skalsky, R.L., Corcoran, D.L., Gottwein, E., Frank, C.L., Kang, D., Hafner, M., Nusbaum, J.D., Feederle, R., Delecluse, H.J., Luftig, M.A., Tuschl, T., Ohler, U., Cullen, B.R. (2012). “The viral and cellular microRNA targetome in lymphoblastoid cell lines.” PLoS Pathog. 8: e1002484. [Abstract] [PDF]

  • Forte, E., Salinas, R., Chang, C., Zhou, T., Linnstaedt, S.D.,  Gottwein, E., Jacobs, C., Jima, D., Li, Q.J., Dave, S.S., Luftig. M.A. (2012). The Epstein-Barr virus induced tumor suppressor miR-34a is growth promoting in EBV-infected B cells. J Virol. 86, 6889-6898. [Abstract] [PDF]

  • Forte, E., Luftig, M.A. (2011). “The role of microRNAs in Epstein-Barr virus latency and lytic reactivation.” Microbes Infect. 13:1156-1167. [Abstract] [PDF]

  • Nikitin, P.A, Luftig, M.A. (2011). “At a crossroads: Human DNA tumor viruses and the host DNA damage response.”  Future Virol. 6: 813-830. [Abstract] [PDF]
  • Nikitin, P.A., Yan, C.M., Forte, E., Bocedi, A.,  Tourigny, J.P., Hu, K.,  Guo, J., Tainter, D., Rusyn, E. and Luftig, M.A. (2010). “An ATM/Chk2-mediated DNA damage responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells.” Cell Host Microbe. Dec 16;8(6):510-22. [Abstract] [PDF]
  • Linnstaedt, S.D., E. Gottwein, R.L. Skalsky, Luftig, M.A., and Cullen, B.R. (2010). "Virally induced cellular miR-155 plays a key role in B-cell immortalization by EBV." J Virol. Nov;84(22):11670-11678. [Epub 2010 Sept 15]. [Abstract] [PDF]

  • Forte, E. and Luftig, M.A. (2009). "MDM2-dependent inhibition of p53 is required for Epstein-Barr virus B cell growth transformation and infected cell survival." J Virol. (2009). 83:2491-2499. [Epub 2009 Jan 14]. [Abstract] [PDF]