Holly Jakubowski 2007 - Saint Anselm College
2007 - Saint Anselm College
Assists in elucidating the mechanisms involved in regulating alternative splicing of IL-7R (Interleukin-7 receptor). It is known there is a SNP (single nucleotide polymorphism) in the gene encoding IL-7R and having this SNP raises one's risk for developing Multiple Sclerosis. If we can understand how to tip the biologic scales towards the membrane bound versus the soluble isoform this may give way to novel therapeutic opportunities.