Rafael K. Campos
2011 - Programa de PG em Educação da PUC Minas (PUC-MG)
Rafael Campos did his undergraduate training in Virus Laboratory, Microbiology Department, UFMG, Brazil, under the direction of Dr. Jônatas Santos Abrahão. He studied poxviruses and helped in the discovery and characterization of previously unknown Vaccinia virus strains and hosts. He also did training in the Calcium Signaling Laboratory, Physiology Department, UFMG, under the direction of Dr. Maria de Fátima Leite. After he earned his bachelor degree from PUC-MG, in 2011, he researched giant viruses in the Department of Microbiology, UFMG, Brazil, under the direction of Dr. Jônatas Santos Abrahão.
In the fall of 2012, Rafael joined the Duke Molecular Genetics and Microbiology PhD program and in 2013 he joined the Garcia-Blanco laboratory as a graduate student, where his broad research goal is to understand host-pathogen interactions of Flavivirus.
Viruses of the genus Flavivirus are single-stranded RNA viruses that are transmitted by arthropod vectors and especially by ticks and mosquitoes, which is the case for the causative agents of dengue, yellow fever, Japanese B encephalitis, Saint Louis encephalitis and West Nile fever. Many of these viruses cause high health impacts, as is the case for Yellow Fever virus, which has an extremely high mortality rate; and Dengue virus, which infects millions of people every year in many different countries, and could be expanding towards the US.
My broad research interest is to understand molecular host-pathogen interactions of the human host with viruses of the Flaviviridae family, by using genome-wide databases generated at the Garcia-Blanco lab to identify host-factors that are essential for viral replication. More specifically, I am currently studying how some ribosomal proteins could be important for viral replication.
Campos RK, Brum MC, Nogueira CE, Drumond BP, Alves PA, Siqueira-Lima L, Assis FL, Trindade GS, Bonjardim CA, Ferreira PC, Weiblen R, Flores EF, Kroon EG, Abrahão JS. Assessing the variability of Brazilian Vaccinia virus isolates from a horse exanthematic lesion: coinfection with distinct viruses.
Arch Virol. 2011 Feb;156(2):275-83. doi: 10.1007/s00705-010-0857-z.
Campos RK, Andrade KR, Ferreira PC, Bonjardim CA, La Scola B, Kroon EG, Abrahão JS. Virucidal activity of chemical biocides against mimivirus, a putative pneumonia agent. J Clin Virol. 2012 Dec;55(4):323-8. doi: 10.1016/j.jcv.2012.08.009.